EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 28-Apr-2025 18:08 ET (28-Apr-2025 22:08 GMT/UTC)

Only half of young cancer patients report a discussion on fertility preservation

Vanderbilt University Medical Center
Peer-Reviewed Publication

Only half of people with early-onset cancers reported discussing fertility preservation options prior to their oncology treatments, according to results of a cross-sectional study published Nov. 12 in JAMA Network Open.

Journal: JAMA Network Open
Funder: NIH/National Cancer Institute, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Center for Advancing Translational Sciences (NCATS), American Cancer Society, Drs. Sidney and Becca Fleischer Undergraduate Summer Research Fund

City of Hope researchers discover why taking a mushroom supplement slows or prevents prostate cancer from getting worse

City of Hope
Peer-Reviewed Publication

City of Hope researchers have discovered that taking a white button mushroom supplement can slow or prevent the progression of prostate cancer. The research, which includes both laboratory and human clinical trial data, shows that the medicinal use of these mushrooms reduces the cells that weaken the immune system and allow prostate cancer to spread.

Journal: Clinical and Translational Medicine

Combination approach shows promise for treating rare, aggressive cancers

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

A research team led by UCLA Health Jonsson Comprehensive Cancer Center investigators has shown that that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with small cell bladder cancer and small cell/neuroendocrine prostate cancer.

Journal: Cell Reports Medicine

DNA packaging directly affects how fast DNA is copied in cells

Hubrecht Institute
Peer-Reviewed Publication

Researchers from the Mattiroli group have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual pathway, affecting the cell’s ability to divide and grow. This opens up new doors to study how the copying of the DNA and its packaging are linked. These findings, published in Molecular Cell, may help scientists to find therapies and medicines for diseases such as cancer in the future.

Journal: Molecular Cell
Funder: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Novo Nordisk Foundation Center for Protein Research, Lundbeck Foundation, Fondazione AIRC per la ricerca sul cancro ETS, ERC, Dutch Cancer Society, NIH director's new innovation award, EU-MUR MSCA Young Researcher, Pew stewart scholar for cancer research Award

Validating an electronic frailty index in a national health system

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY- November 12, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), on October 24, 2024, Volume 16, Issue 20, titled, "Development and validation of an electronic frailty index in a national health maintenance organization."

Journal: Aging-US

Study identifies new approach to overcome docetaxel resistance in patients with advanced prostate cancer

Elsevier
Peer-Reviewed Publication

The treatment landscape for patients with prostate cancer, especially individuals with advanced disease, has dramatically changed in recent years. However, aside from drug or hormonal therapies, other targets to treat prostate cancer are still necessary to prolong life and slow the progression of this potentially lethal disease. A new study in The American Journal of Pathology, published by Elsevier, found that inhibition of the sterol regulatory element of binding (SREB) can reinduce sensitivity to the drug docetaxel, commonly used to treat prostate and other cancers. These findings show promise to improve the efficacy of docetaxel-based chemotherapy in patients with prostate cancer.

Funder: Anniversary Fund of the Oesterreichische Nationalbank, Brigitte und Dr. Konstanze Wegener-Stiftung, Ferdinand-Eisenberger

Extracellular matrix and tumor-immune interactions: challenges & opportunities

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY - November 12, 2024 – A new review was published in Oncotarget's Volume 15 on November 7, 2024, entitled “Understanding the interplay between extracellular matrix topology and tumor-immune interactions: Challenges and opportunities.”

Journal: Oncotarget

Goblet cells could be the guardians of the gut

First Hospital of Jilin University
Peer-Reviewed Publication

Researchers at UC San Diego have examined the critical role of goblet cells in gut immunity and health. GCs create a mucus barrier that protects against pathogens while supporting beneficial bacteria. They also deliver antigens to immune cells, promoting gut tolerance. Disruptions to goblet cell functions can contribute to gastrointestinal diseases like colorectal cancer and inflammatory bowel disease, making them a promising therapeutic target for maintaining gut health and combating various gut-related conditions.

Journal: eGastroenterology
Funder: National Institute of Health Sciences, The San Diego's Hispanic Center of Excellence, NIH/National Institute on Alcohol Abuse and Alcoholism, American Association for the Study of Liver Diseases (AASLD) Pinnacle Research Award in Liver Disease, Isenberg Endowed Fellowship jointly awarded by the Pilot/Feasibility Program of the San Diego Digestive Diseases Research Center (SDDRC), Hellman Family Foundation

Wyss Institute’s iNodes team receives ARPA-H Sprint for Women’s Health award to advance the first implantable immune organs to treat ovarian cancer

Wyss Institute for Biologically Inspired Engineering at Harvard
Grant and Award Announcement

Ovarian cancer is more deadly than any other type of female reproductive organ cancer. It is estimated that in 2024, in the U.S. alone, more than 12,000 women will die from the disease because available therapies are not effective. To help overcome this striking deficit in women’s health, ARPA-H has awarded a team at the Wyss Institute at Harvard University a contract under its Sprint for Women’s Health program to develop “iNodes” – implantable lymphoid organs containing patients’ immune cells – as an entirely novel form of personalized immunotherapy to treat ovarian cancer.

Medicaid enrollment continuity tied to lymphoma stage at diagnosis

American Society of Hematology
Peer-Reviewed Publication

(WASHINGTON, November 12, 2024) – Continuous enrollment in Medicaid was associated with a lower rate of a late-stage lymphoma diagnosis in children and adolescents/young adults (AYAs). However, fewer than half of Medicaid-insured patients in these age ranges were continuously enrolled before diagnosis, according to a study published today in Blood Advances.

Journal: Blood Advances