New understanding of a decades-old bladder cancer treatment could help improve immunotherapies more broadly
Peer-Reviewed Publication
Updates every hour. Last Updated: 27-Oct-2025 21:11 ET (28-Oct-2025 01:11 GMT/UTC)
A team of researchers from MSK and Weill Cornell Medicine is expanding the understanding of how a decades-old treatment for bladder cancer works — an understanding that could help improve the effectiveness of immunotherapies more broadly.
More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.
Now, a team of researchers from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center (MSK) and is expanding the understanding of how the treatment works — an understanding that could help improve the effectiveness of immunotherapies more broadly.
Scientists at St. Jude Children’s Research Hospital have found that genetics and type of cancer treatment contribute most to a survivor’s risk of a second cancer.
A lab-designed molecule developed and extensively studied by scientists with Virginia Tech’s Fralin Biomedical Research Institute at VTC could represent a breakthrough in slowing tumor recurrence in glioblastoma, an aggressive and deadly form of brain cancer.