In a paper published in National Science Review, an international team of scientists report a coordination nanomedicine (ZnDHT NM) featuring cascade specific Fe³⁺ capturing and in situ catalysis for achieving tumor catalysis-enhanced differentiation therapy. This nanomedicine can simultaneously treat cancer stem-like cells (CSCs) and bulk tumor cells by interfering with tumor Fe metabolism and redox homeostasis, thereby effectively inhibiting tumor growth, recurrence and metastasis.

This study utilizes bibliometric analysis to investigate the research landscape of FAP-directed cancer theranostics, focusing on the development and application of radiotracers based on quinoline-based FAP inhibitors (FAPIs).

A team of researchers have made a new discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

Collaborators Dr Jing Jing Wang (co-first author), Professor Tom Gordon, and colleagues from Flinders University played a key role in cracking the code of lethal blood antibodies mediating the new chronic blood clotting disorder.

The new study led by Professor Ted Warkentin from McMaster University in Canada was published in the leading international medical journal, The New England Journal of Medicine.

The findings are expected to influence how doctors test for, and treat patients with, unusual or recurrent blood clotting, with the potential to improve patient outcomes.

 Aging is a privilege, but it also brings risks—including an increased likelihood of developing age-related diseases including cancer. Researchers at The Jackson Laboratory (JAX) have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development. Their findings, published recently in Nature Aging, provide a valuable open-access resource for the scientific community to explore aging and its role in increased cancer risk.