Dysregulation of non-coding RNAs (ncRNAs) promotes pancreatic cancer growth, metastasis, treatment resistance, and cancer stemness. To shed light on the mechanisms behind their dysregulation, researchers from China, conducted a scientific review that summarizes how ncRNAs are involved in pancreatic cancer progression. Their study highlights that ncRNAs can act as scaffolds, promoting protein-protein/nucleotide interactions, as protein sponges that limit protein interactions, and by translocating proteins to various subcellular compartments.

Acute myeloid leukemia (AML) remains one of the most aggressive and deadly forms of blood cancer, even as treatments have advanced in recent years. Standard approaches like high-dose chemotherapy and bone marrow transplants can extend life but often come at the cost of severe side effects — and many patients still relapse due to drug-resistant cancer cells. A research team led by Natasha Kirienko at Rice University is working to change that by turning the cancer cells’ own energy systems against them.