SUGAR LAND, Texas ― The University of Texas MD Anderson Cancer Center today broke ground on a new 470,000-square-foot facility in Sugar Land, bringing a range of cancer services and MD Anderson’s unparalleled patient experience closer to those living in Southwest Houston and the surrounding areas.

As warehouses go, nuclei are more like libraries than bank vaults. Too many cellular components need access to the genome to lock it down like Fort Knox. Instead, large groupings of more than 1,000 individual protein molecules called nuclear pore complexes (NPCs) pepper the dividing membrane, serving as gateways for materials and messages entering and exiting the nucleus.

A new study on the genetic causes of the PTEN Hamartoma Tumour Syndrome (PHTS) has found that inhibitors of the PI3ka pathway, commonly used as anticancer drugs, are also effective against this disease, reducing the extent of vascular malformations and lesion-associated pain in animal models. The research, led by Dr. Sandra Castillo, Dr. Eulàlia Baslega and Dr. Mariona Graupera, from the SJD Pediatric Cancer Center Barcelona, Hospital Sant Joan de Déu, and the Josep Carreras Leukaemia Research Institute, respectively, suggests the repurposing of these drugs may offer a new hope for PHTS patients, especially at younger ages. The research has been published in Cancer Discovery, a journal of the American Association for Cancer Research.

This study explores the relationship between gallstones, cholecystectomy, and cancer risk through both observational and Mendelian randomization (MR) methods. The research aims to clarify the inconsistent findings from previous studies regarding the association of gallstones and cholecystectomy with various types of cancers, particularly in Chinese adults.