Scientists have captured the most detailed structural images to date of a specific type of protein’s DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers.

UC Irvine-led study found that exposure to previously unknown PFAS chemicals was associated with a higher risk of acute lymphoblastic leukemia, the most common childhood cancer.

Researchers analyzed blood samples from 125 newborn children with leukemia and 219 without cancer in Los Angeles County, also finding higher levels of PFOA and PFOS linked to increased risk.

The study builds on earlier research linking PFAS in drinking water to childhood cancers and calls for further study as exposure remains widespread.

Randomized trial found newer screening test had a greater uptake among participants, but increasing follow-up colonoscopy tests remain a priority

Conventional wisdom holds that lower cholesterol is better for heart health, but new Views & Comments in Engineering challenges this idea. A large cross‑ethnic study finds a U-shaped cholesterol–mortality link in Chinese adults: both very low and high levels raise death risk, with low levels linked to higher cancer and hemorrhagic stroke risk. Optimal cholesterol levels differ between Chinese and UK adults, calling for personalized, population-tailored management.