BUFFALO, NY – July 18, 2025 – A new editorial was published in Volume 16 of Oncotarget on July 16, 2025, titled “microRNAs in soft tissue sarcoma: State of the art and barriers to translation.”

A new study introduces an AI-integrated dynamic biomarker system that detects early disease tipping points and classifies thyroid cancer into actionable subtypes, paving the way for precision diagnosis and treatment.

This comprehensive review highlights the compositional and functional heterogeneity of intratumoral microbiota within the tumor microenvironment (TME), and their implications in tumorigenesis and cancer progression. The findings underscore the dual roles of these microbes in modulating immune responses and metabolic processes, offering new directions for cancer diagnostics and therapeutic interventions.

Histopathology is the gold standard in cancer diagnosis. However, attenuated total reflectance (ATR)-Fourier transform infrared (FTIR) spectroscopy has shown diagnostic potential in other settings. Therefore, this study aimed to investigate the sensitivity and specificity of the ATR-FTIR spectroscopy in evaluating breast lesions.

BUFFALO, NY — July 18, 2025 — A new case report was published in Volume 12 of Oncoscience on July 2, 2025, titled “Navigating diagnostic complexity: A case report on uterine lipoleiomyoma, unveiling its benign nature amidst characteristics resembling liposarcoma.”

A nationwide study published in eGastroenterology reveals that while age-standardised mortality from digestive system malignancies (DSMTs) has declined in China between 2004 and 2021, significant disparities persist by cancer type, gender, and region. Oesophageal, gastric, and liver cancer rates decreased, reflecting effective public health interventions. In contrast, mortality from pancreatic and colorectal cancers rose, especially in males and rural populations. The study also highlights improvements in life expectancy and reductions in premature mortality from DSMTs. However, persistent inequities underline the need for targeted cancer prevention, improved screening, and equitable healthcare access.

When fermented with plant-derived bacteria, stevia leaf extract is toxic to pancreatic cancer cells but not to healthy kidney cells

Modern methods of radiotherapy would fight cancer more effectively and safely if treatments could be planned taking into account the radiation quality of the therapeutic proton beams. An achievement by physicists from the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow brings us closer to this goal.

Borrowing from the anti-inflammatory properties of olive oil, Penn Engineers used a century-old chemical reaction to redesign the lipid nanoparticles that deliver mRNA. By adding phenol groups, antioxidant compounds found in olive oil, to the delivery molecules, they created a new class of lipids that reduce inflammation and enhance performance. The result is a safer, more effective platform for mRNA vaccines and therapies, with promising results in animal models of COVID-19, cancer and gene editing.