Revolutionizing cancer research: human tumor organoids bridge the gap between lab and clinic
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 20:15 ET (23-Jun-2026 00:15 GMT/UTC)
Human tumor organoids have advanced cancer modeling by preserving patient-specific heterogeneity and functional drug responses. However, translating organoid findings into routine decision-making remains challenging due to variability in culture conditions and incomplete reconstruction of the tumor microenvironment. In this review, we present a clear and actionable framework that positions tumor organoids as dynamic living biosensors, linking mechanistic studies, tumor microenvironment reconstruction, functional drug-response phenotyping, and precision-therapy decision-making.
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