A research team led by The Hong Kong University of Science and Technology (HKUST) has developed a pioneering artificial intelligence (AI) pathology analysis system that can accurately recognize multiple types of cancer using only a minimal number of samples—without requiring any additional training. This breakthrough significantly enhances the flexibility and efficiency of AI-assisted medical care, marking a major step forward toward the widespread adoption of intelligent pathology.

An international team of researchers, led by Peggi Angel, Ph.D., at MUSC Hollings Cancer Center, mapped the biology of healthy breast tissue and uncovered early molecular changes in collagen, the tissue’s structural framework, linked to cancer risk. Their findings show that breast tissue is not uniform; rather, it is made up of dynamic microenvironments shaped by factors like body weight and breast density.

This work suggests that cancer develops gradually – offering new opportunities for earlier detection, more personalized screening and improved prevention strategies.

New research from Boston Children’s Hospital, published in Cell, finds that the brain’s resident immune cells, microglia, amass mutations in specific cancer-driving genes yet they don’t manifest as cancer. Instead, these mutations may help drive Alzheimer’s disease. These findings may provide insights into new Alzheimer’s disease diagnostics and treatments.

Precancerous oral lesions can progress to oral cancer and are typically ablated or surgically removed as a preventive measure

Direct injection of nivolumab immunotherapy into lesions reduced toxicities and reduced lesion size by an average of 60%, decreasing the risk of cancer progression

More than 80% of treated lesions were cancer-free after one year, and patients reported improved quality of life and tolerable side effects

Direct injection approach offers benefits over systemic nivolumab, which could bring excessive toxicities for patients without cancer