EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 26-Oct-2026 21:16 ET (27-Oct-2026 01:16 GMT/UTC)

Stereotactic body radiotherapy vs moderately hypofractionated IMRT for localized intermediate-risk prostate cancer

JAMA Network
Peer-Reviewed Publication

About the Study: In this randomized clinical trial of 698 patients with localized intermediate-risk prostate cancer, stereotactic body radiotherapy was not superior to moderately hypofractionated IMRT for disease-free survival at 3 years. SBRT was associated with better bowel-related quality of life, but cancer control was not improved.

Journal: JAMA

Metabolic dysfunction after initiation of androgen receptor pathway inhibitors in prostate cancer

JAMA Network
Peer-Reviewed Publication

About the Study: In this retrospective cohort study of 16,924 men with prostate cancer starting concurrent androgen deprivation therapy and an androgen receptor pathway inhibitor, metabolic syndrome and related abnormalities were frequently documented during the first year of treatment. Hypertension was the most common metabolic outcome.

Journal: JAMA Oncology

Focal therapy for prostate cancer

JAMA Network
Peer-Reviewed Publication

About the Study: This retrospective study uses data from the National Cancer Database to examine patterns and temporal trends in use of focal therapy for prostate cancer in US cancer centers. In a cohort of about 1.18 million patients with nonmetastatic prostate cancer, about half of focal therapy procedures occurred in low-, high-, or very-high-risk disease, settings in which routine use is not supported by current guidelines. Overall use remained uncommon.

Journal: JAMA

For early prostate cancer ‘active surveillance’ is now #1 choice

University of California - San Francisco
Peer-Reviewed Publication

Three decades after UC San Francisco pioneered “active surveillance” for patients with low-risk prostate cancer, a new study has found that the vast majority of veterans with the diagnosis pursued this option instead of treatment.

Journal: JAMA

Couple coping may ease depression after gastrointestinal cancer

Maximum Academic Press
Peer-Reviewed Publication

A research team has found that dyadic coping—the way couples jointly manage stress—partly explains the association between fear of cancer recurrence and depression among middle-aged and older survivors of gastrointestinal cancer.

Journal: European Journal of Cancer Care

Damon Runyon Cancer Research Foundation awards $4.2 million to exceptional early-career scientists

Damon Runyon Cancer Research Foundation
Grant and Award Announcement

The Damon Runyon Cancer Research Foundation has named 14 new Damon Runyon Fellows, brilliant postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

ASTRO updates guideline on radiation therapy for pancreatic cancer

American Society for Radiation Oncology
Peer-Reviewed Publication

An updated clinical guideline from the American Society for Radiation Oncology (ASTRO) provides evidence-based recommendations on the use of radiation therapy to treat adult patients with pancreatic cancer. The guideline updates ASTRO’s 2019 recommendations to reflect recent clinical trials that provide growing evidence for radiation therapy in the resectable, locally advanced and metastatic settings. It was published in Practical Radiation Oncology, ASTRO’s clinical practice journal

Journal: Practical Radiation Oncology

Making cancer treatment precise with a ‘locking’ therapeutic

American Chemical Society
Peer-Reviewed Publication

Although there are many cancer treatments available today that effectively eliminate abnormal cells, these therapies may also damage healthy cells, leading to unwanted side effects. Now, researchers publishing in ACS’ Journal of Medicinal Chemistry have developed a new therapeutic that is kept “locked” unless it finds itself within a tumor cell. In mice, the treatment significantly reduced tumor size without accumulating in the liver, which suggests adverse exposures could be reduced and treatment safety improved.

Journal: Journal of Medicinal Chemistry

Fabrication of flexible microsystem for prospective photodynamic therapy applications

Editorial Office of Opto-Electronic Journals Group
Peer-Reviewed Publication

This research explores a new wireless implantable device designed to improve photodynamic therapy (PDT) for cancer treatment, particularly bladder cancer. By delivering light directly inside the body without wires, the system helps overcome the challenge of limited light penetration in traditional PDT. The study shows that the device can successfully generate the key molecules needed to destroy cancer cells, offering a promising step toward more precise, less invasive treatments in the future.

Journal: Opto-Electronic Advances
Funder: Engineering and Physical Sciences Research Council

NUS scientists uncover ‘hidden switch’ that helps cancer cells hide from the immune system

National University of Singapore
Peer-Reviewed Publication

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered a previously unknown mechanism that helps cancer cells evade detection by the body’s immune system. The finding could pave the way for development of more effective cancer immunotherapies.

Journal: Science Immunology

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