EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 22-Jun-2026 01:15 ET (22-Jun-2026 05:15 GMT/UTC)

Scripps Research scientists uncover new mechanism cancer cells use to survive DNA damage

Scripps Research Institute
Peer-Reviewed Publication

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

Journal: Molecular Cell

Researchers study shifts in cancer mortality

Mississippi State University
Peer-Reviewed Publication

Researchers at Mississippi State's Social Science Research Center, in partnership with scientists at Oak Ridge National Laboratory, analyzed cancer deaths in almost 3,000 U.S. counties from 1981-2019, finding urban and affluent counties were more likely to experience a significant decline in cancer mortality.

Journal: British Journal of Cancer

Four Keck School of Medicine of USC researchers elected as senior members of the National Academy of Inventors

Keck School of Medicine of USC
Grant and Award Announcement

The National Academy of Inventors (NAI), a nonprofit member organization that promotes academic technology and innovation, has named four Keck School of Medicine of USC faculty as new senior members: Paula Cannon, PhD; Alan Epstein, MD, PhD; Heinz-Josef Lenz, MD; and Bodour Salhia, PhD.

The new senior members will be welcomed at the 2026 NAI conference, hosted by USC at Loews Hollywood Hotel from June 1 to 4.

NAI senior members are recognized for their work producing innovative technologies that have the potential for real impact on the welfare of society, as well as success in patents, licensing and commercialization. This year’s members from the Keck School of Medicine are being recognized for their innovations in cancer and HIV.

Meeting: 2026 National Academy of Inventors conference

Trends and disparities in the use of next-generation sequencing in patients with cancer in the US

JAMA Network
Peer-Reviewed Publication

About The Study: In this cohort study, most patients with advanced or metastatic cancers did not undergo tumor genomic testing. Low socioeconomic status, Black race or Hispanic ethnicity, and Medicaid or Medicare coverage were associated with significantly longer time to next-generation sequencing, highlighting the need for awareness and health care policies aimed at bridging these gaps.

Journal: JAMA Network Open

Researchers develop AI tool to predict Barrett’s esophagus recurrence after therapy

University of Colorado Anschutz
Peer-Reviewed Publication

A new artificial intelligence (AI)–based tool shows promise for improving surveillance in patients treated with endoscopic eradication therapies for Barrett’s esophagus (BE) related dysplasia and early esophageal adenocarcinoma. BE, is the only known condition that precedes esophageal adenocarcinoma - an aggressive cancer with high mortality rates.

Developed and validated by U.S. researchers, the AI model was over 90% accurate at predicting which patients would experience a recurrence of BE after endoscopic eradication therapy (EET) and detecting when it’s likely to occur.

The findings were published today in Clinical Gastroenterology and Hepatology.

Journal: Clinical Gastroenterology and Hepatology

Study identifies PHIP as a novel dependency in cancers driven by SWI/SNF mutations

St. Jude Children's Research Hospital
Peer-Reviewed Publication

Discover research from St. Jude identifying PHIP as a novel dependency in cancers that have mutations in SWI/SNF

Journal: Nature Communications

Adjuvant PD-1/PD-L1 inhibitors show efficacy but highlight safety considerations in solid cancers

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY – April 7, 2026 – A new research paper was published in Volume 17 of Oncotarget on March 31, 2026, titled “Efficacy and safety of PD-1/ PD-L1 inhibitors as adjuvants in the treatment of patients with solid cancers: A systematic review and meta-analysis of randomized controlled trials.”

Journal: Oncotarget

Lactylation modification drives lung cancer progression and drug resistance

FAR Publishing Limited
Peer-Reviewed Publication

A new review highlights how lactylation—a lactate-induced protein modification—drives lung cancer progression, immune escape, and therapy resistance. It details the “writer-eraser-reader” regulatory network and self-reinforcing feedback loops, offering new therapeutic targets and biomarker strategies to overcome resistance in lung cancer.

Journal: Current Molecular Pharmacology

Natural alkaloid gramine suppresses triple-negative breast cancer by inducing ferroptosis via the CUL3–MTDH axis

FAR Publishing Limited
Peer-Reviewed Publication

Researchers found that gramine, a natural indole alkaloid, selectively inhibits triple-negative breast cancer by inducing ferroptosis. It directly binds CUL3, reducing MTDH ubiquitination and stabilizing MTDH, which downregulates GPX4 and SLC3A2. This study highlights a novel CUL3–MTDH–ferroptosis axis and positions gramine as a promising TNBC therapeutic candidate.

Journal: Current Molecular Pharmacology

NCCN announces first fellows for new advocacy academy to help drive effective cancer policy

National Comprehensive Cancer Network
Grant and Award Announcement

The NCCN Advocacy Academy is a new program launched in 2026 to ensure that voices of oncology professionals are present at the health policy decision-making table. The NCCN Policy Team selected 12 doctors to participate in this first year.

88
89
90
91
92