Toward autonomous nano-manipulation robots: Integrated SEM systems enable atomic-scale fabrication
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Jan-2026 09:11 ET (21-Jan-2026 14:11 GMT/UTC)
The article highlights how integrated platforms—especially within scanning electron microscopes (SEM)—are enabling multi-degree-of-freedom, closed-loop nano-robots capable of precise assembly and manufacturing at the atomic scale. These advances pave the way for breakthroughs in quantum devices, nanomedicine, and advanced materials.
Meta-holograms with nano-structured metasurfaces enable efficient light recording, offering high capacity for information storage and imaging. Scientists in China provided a full-modulation metasurface strategy for robust and scalable multi-dimensional multiplexing meta-holography. This metasurface allows independent and arbitrary control of amplitude, phase, and polarization of spatial light, enabling precise construction of multiplexed holograms. The method showcases a potential for optical information storage, transmission, and encryption applications.
Surgeons in Vietnam successfully applied refinements to a little-used flap technique to reconstruct a patient’s thumb after a severe motorcycle injury. By preserving subcutaneous tissue and creating a safe arterial margin, the team improved blood flow, reduced complications, and restored nearly full thumb function within a year. Their preliminary case report suggests these refinements may make the reverse homodigital dorsoradial flap a more reliable option for thumb reconstruction.
This review synthesizes the utility of exhaled volatile organic compounds (VOCs) in cancer diagnosis, treatment efficacy prediction, and recurrence monitoring. As endogenous metabolic byproducts, VOCs enable noninvasive detection via technologies like gas chromatography-mass
spectrometry (GC-MS), electronic noses, selected ion flow tube mass spectrometry (SIFT-MS), and high-pressure photonionization time-of-flight mass spectrometry (HPPI-TOFMS).
Key findings include strong diagnostic performance (e.g., lung cancer AUC=0.95, hepatocellular carcinoma VOC sensitivity outperforming AFP),accurate prediction of anti-PD-1/PD-L1 therapy response (AUC=0.89–0.97), and utility in colorectal cancer postoperative recurrence surveillance. Innovatively, it links VOC alterations to mechanisms (oxidative stress, CYP450 overexpression) and compares detection technologies’ strengths/limitations.
Clinical implications: VOCs address gaps of traditional biomarkers (low sensitivity/specificity), while highlighting needs for standardized sampling/analysis protocols and improved device stability to advance clinical translation.
Fruit softening determines the texture, shelf life, and consumer appeal of grapes, yet its molecular regulation remains largely unknown.
Haploid plants, which carry only a single set of chromosomes, are typically sterile, making them valuable but difficult to use in breeding.
Theanine, a unique amino acid responsible for tea's refreshing taste and calming effect, plays a central role in determining tea quality.