A new clinical trial published in the Chinese Medical Journal has assessed a novel triple-combination regimen comprising the angiogenesis inhibitors famitinib, the cyclin-dependent kinase 4/6 (CDK4/6) inhibitor dalpiciclib, and fulvestrant for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2−) advanced breast cancer. Although the regimen exhibited measurable antitumor activity, its overall efficacy and safety profile did not support its use as a preferred first-line therapeutic option. 

Precision forestry has long lacked a reliable way to predict how light moves through tree canopies over time—a gap that limits everything from pruning decisions to yield optimization. 

A review traces One Health from historical disease-control lessons to today’s interconnected threats and proposes an “interface-resilience” model. The model links spillover pressure, microbial community stability and governance connectivity to systemic health risk, offering a framework for earlier warning, cross-sector surveillance and preventive, data-driven health governance.

A new review proposes the psycho-cardiovascular interaction network (PCIN), a framework that links psychological and psychiatric factors with cardiovascular health and disease.

The Moon no longer has a global magnetic field, but lunar rocks and soils still contain records of ancient magnetism. Therefore, studying the magnetic minerals in these samples can help scientists understand how the Moon’s magnetic field evolved over time. Recently, researchers examining impact-glass particles containing metallic iron from Chang’e-6 lunar soil samples discovered face-centered cubic γ-Fe—the first time this iron phase has been identified in natural lunar samples.

Coronary artery disease remains the top global cause of death, yet standard angiography cannot visualize dangerous artery plaque, creating gaps for guiding percutaneous coronary intervention. This narrative review synthesizes 10 years of human studies, clinical trials and consensus documents covering established and emerging intravascular imaging plus computational tools. Hybrid catheter systems have completed first‑in‑human testing, while artificial‑intelligence plaque analysis delivers diagnostic accuracy comparable to expert readers. These technologies enable combined anatomical, compositional and functional vessel assessment, though broad clinical roll‑out still requires standardized validation and streamlined workflow integration.

A research team has uncovered a compact gene cluster that helps Camptotheca acuminata produce two valuable classes of specialized metabolites: camptothecin derivatives and flavonoids.

Pumpkin is a global food security crop prized for its nutritional value, stress tolerance, and long shelf life. 

Emerging Contaminants is a leading platform for research addressing the potential ecological and human health risks associated with environmental contamination from emerging contaminants.

This article collection features papers published in Environmental Surfaces and Interfaces since 2025 on the theme of materials-driven environmental pollutant removal. It focuses on the development of novel materials and their practical applications in environmental pollutant remediation. All articles are freely available for reading.