A research paper by scientists at Peking University Third Hospital proposed a parameter-adjustable photobiomodulation (PBM) therapy apparatus to screen for the optimal PBM parameters for treating ischemic stroke and preventing post-stroke cognitive impairment (PSCI).

The new research paper, published on May. 6 in the journal Cyborg and Bionic Systems, provide a PBM therapy apparatus with custom parameters. By evaluating the treatment effect, we identified that 755 nm was the optimal light wavelength for ischemic stroke in rats with transient middle cerebral artery occlusion/reperfusion.

Recently, the team led by Chief Physician Quan Zhang and Associate Professor Feng Liu at Tianjin Medical University General Hospital systematically evaluated the genetic associations between type 2 diabetes mellitus and subcortical brain structures using large-scale genome-wide association summary statistics and advanced statistical genetic methods. The related findings were published in Research under the title "Genome-wide pleiotropy analysis reveals shared genetic associations between type 2 diabetes mellitus and subcortical brain volumes".

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects in IVD function lead to toxic accumulation of metabolites such as isovaleric acid, resulting in isovaleric acidemia (IVA)—a life-threatening autosomal recessive disorder characterized by vomiting, metabolic acidosis, and neurological damage. Although IVD gene mutations are known to cause IVA, the enzyme's structural dynamics and complex substrate-binding mechanisms have long hindered precise mechanistic studies.

Among various technologies, anion exchange membrane water electrolysis (AEMWE) has emerged as a major research focus due to its significant cost advantages and commercialization potential. By utilizing non-precious metal electrocatalysts, AEMWE successfully combines the high efficiency of proton exchange membranes with the mature process advantages of conventional alkaline electrolysis, while potentially overcoming their respective technical limitations, demonstrating broad application prospects.