EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 6-May-2025 23:09 ET (7-May-2025 03:09 GMT/UTC)

21-Jan-2025

Deep learning model helps detect lung tumors on CT

Radiological Society of North America
Peer-Reviewed Publication

A new deep learning model shows promise in detecting and segmenting lung tumors. The findings of the study could have important implications for lung cancer treatment.

Journal: Radiology

21-Jan-2025

Telephone therapy reduces fatigue interference with activities, mood and cognition for metastatic breast cancer survivors

Regenstrief Institute
Peer-Reviewed Publication

A clinical trial demonstrates the effectiveness of telephone-delivered acceptance and commitment therapy (ACT) in reducing fatigue’s interference with functioning and improving the quality of life for survivors of metastatic breast cancer. The ACT intervention helped study participants to fall asleep with greater ease. Fatigue remains a significant challenge for these survivors, affecting up to 63 percent of patients and severely impacting daily functioning.

Journal: Journal of Clinical Oncology
Funder: NIH/National Cancer Institute

21-Jan-2025

Anti-correlation between KLRG1 and PD-1 in tumor CD8 T cells

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY - January 21, 2025 – A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled “Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells."

Journal: Oncotarget

21-Jan-2025

Chinese Medical Journal review highlights senescence’s dual role in liver disease and emerging therapies

Chinese Medical Journals Publishing House Co., Ltd.
Peer-Reviewed Publication

Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, researchers from China examined the mechanisms behind senescence, its impact on liver cells, and its contribution to liver diseases like metabolic dysfunction-associated steatohepatitis (MASH), cirrhosis, and hepatocellular carcinoma. The review also highlights the potential of senolytic therapies, which target senescent cells to reduce damage, offering hope for improved liver disease treatments.

Journal: Chinese Medical Journal

21-Jan-2025

Early diagnosis of bladder cancer, now conveniently at home

National Research Council of Science & Technology
Peer-Reviewed Publication

The research team led by Dr. Youngdo Jeong of the Center for Advanced Biomolecular Recognition the Korea Institute of Science and Technology (KIST), in collaboration with Professor Seok-Ho Kang’s team from the Department of Urology, Korea University College of Medicine, has developed a urine-based diagnostic kit for bladder cancer that can be conveniently used at home. This kit can accurately detect bladder cancer biomarkers without any preprocessing of urine samples.

Journal: Nature Biomedical Engineering
Funder: Ministry of Science and ICT

20-Jan-2025

Gene classifier tests for prostate cancer may influence treatment decisions despite lack of evidence for long-term outcomes

American College of Physicians
Peer-Reviewed Publication

A systematic review found that while genomic classifier (GC) tests may influence risk classifications or treatment decisions for patients with localized prostate cancer (PCa), there is a need for better data on their cost-effectiveness, clinical utility, and their impact on racial and ethnic groups, particularly Black men.

Journal: Annals of Internal Medicine

20-Jan-2025

HKU research identifies PICH protein as key player in preventing chromosome breakage linked to cancer

The University of Hong Kong
Peer-Reviewed Publication

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

Led by Professor Gary Ying Wai CHAN from the School of Biological Sciences, Faculty of Science, and Professor Ken Hoi Tang MA from the Department of Pathology, LKS Faculty of Medicine, the research uncovers the vital role of a protein called PICH in preventing genetic errors that can lead to diseases such as cancer. Their findings were recently published in the journal Nucleic Acids Research.

Journal: Nucleic Acids Research

20-Jan-2025

New study paves way for immunotherapies tailored for childhood cancers

Karolinska Institutet
Peer-Reviewed Publication

Researchers at Karolinska Institutet and the Astrid Lindgren Children’s Hospital in Sweden have determined how children’s immune systems react to different kinds of cancer depending on their age. The study, which is published in the journal Cell, reveals significant differences between the immune response of children and adults, and has the potential to lead to new tailored treatments for children with cancer.

Journal: Cell

20-Jan-2025

Printing proteins to recreate the gut in the lab

Institute for Bioengineering of Catalonia (IBEC)
Peer-Reviewed Publication

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and villi in the intestine using a contact protein printing technique. This model will make it possible to study in detail key processes such as cell regeneration or changes associated with diseases such as cancer and chronic inflammatory disorders.

Journal: Nature Communications
Funder: European Research Council, Generalitat de Catalunya, Spanish Ministry of Economy and Competitiveness

20-Jan-2025

Prognostic power of the micropapillary pattern in pancreatic ductal adenocarcinoma: A game changer

Xia & He Publishing Inc.
Peer-Reviewed Publication

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy characterized by distinct histological subtypes and a poor prognosis. Among these, the micropapillary pattern, typically observed focally, has been associated with worse outcomes in various cancers. This study aimed to evaluate the prognostic significance of the micropapillary pattern in PDAC, focusing on its percentage within the tumor and its impact on overall survival.

Journal: Journal of Clinical and Translational Pathology