EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 9-Sep-2025 22:11 ET (10-Sep-2025 02:11 GMT/UTC)

New ACS study: Late-stage incidence rates continue to increase rapidly as mortality declines slow

American Cancer Society
Peer-Reviewed Publication

Today, the American Cancer Society (ACS) released Prostate Cancer Statistics, 2025, a report on current prostate cancer occurrence and outcomes in the United States. According to the study, prostate cancer incidence rates have reversed from a decline of 6.4% per year during 2007 through 2014 to an increase of 3.0% annually during 2014 through 2021, with the steepest increase (4.6%-4.8% per year) for advanced-stage diagnoses. Simultaneously, mortality declines slowed from 3%-4% per year during the 1990s and 2000s to 0.6% per year over the past decade. These major findings are to be published today in the journal CA: A Cancer Journal for Clinicians.

Shorter, less intense radiation-chemo regimen effective for HPV-linked oropharyngeal cancer, Mayo study shows

Mayo Clinic
Peer-Reviewed Publication

A Mayo Clinic study finds that a shortened, less intense course of radiation and chemotherapy after minimally invasive surgery for HPV-positive oropharyngeal squamous cell carcinoma (HPV+OPSCC) results in less toxicity, substantially lowering the rates of treatment-related side effects while maintaining high cure rates. The findings were published in The Lancet Oncology.

Journal: The Lancet Oncology

Therapeutic vaccination against HPV-related tumors: Nanoparticles make the difference

German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)
Peer-Reviewed Publication

Researchers from the German Cancer Research Center (DKFZ) have collaborated with the SILVACX project group at Heidelberg University to develop a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. The team showed that virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse model, the nanoparticle-based vaccine was able to partially or completely suppress HPV-related tumors.

Journal: OncoImmunology

New research identifies a natural guardian of blood vessel health

MDI Biological Laboratory
Peer-Reviewed Publication

Summary/Description (1–2 sentences):
An international research team led by MDI Biological Laboratory has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessel integrity. Published in Arteriosclerosis, Thrombosis, and Vascular Biology, the findings suggest Hpa2 may provide a natural mechanism to prevent and treat diseases linked to vascular leakiness, including diabetic retinopathy, macular degeneration, kidney disease, cardiovascular disease, and cancer.

Journal: Arteriosclerosis Thrombosis and Vascular Biology
Funder: Scott MacKenzie Foundation, German Research Foundation (DFG), NIH/National Institute of General Medical Sciences, NIH/National Institute of General Medical Sciences

New genetic biomarker flags aggressive brain tumors

Mayo Clinic
Peer-Reviewed Publication

Clinicians typically classify meningiomas — the most common type of brain tumor — into three grades, ranging from slow-growing to aggressive. But a new multi-institutional study suggests that appearances may be deceiving. If a tumor shows activity in a gene called telomerase reverse transcriptase (TERT), it tends to recur more quickly, even if it looks low-grade under the microscope.

Journal: The Lancet Oncology

AI effective at detecting advanced breast cancer, but misses some cases

Korea University College of Medicine
Peer-Reviewed Publication

A Korean research team has reported that artificial intelligence (AI) used in mammography missed 14% of invasive breast cancers, the type where delayed diagnosis can directly impact patient survival.

Journal: Radiology

Brain cancer cells can be ‘reprogrammed’ to stop them from spreading

University of Cambridge
Peer-Reviewed Publication

Scientists have found a way to stop brain cancer cells spreading by essentially ‘freezing’ a key molecule in the brain.

Journal: Royal Society Open Science

Researchers develop multimodal deep learning model to enhance precision radiotherapy decision-making

Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Peer-Reviewed Publication

Researchers developed a deep learning-based multimodal prognostic model that shows strong potential to improve disease-free survival prediction and enable personalized treatment in locally advanced cervical cancer.

Journal: npj Digital Medicine

Pioneering strategy may keep breast cancer from coming back

University of Pennsylvania School of Medicine
Peer-Reviewed Publication

A first-of-its-kind clinical trial identified risk of breast cancer recurrence and successfully treated dormant tumor cells using existing drugs.

Journal: Nature Medicine

Study reveals global inequalities in cancer research funding

University of Southampton
Peer-Reviewed Publication

Researchers at the University of Southampton examining worldwide variations in funding for cancer research say there’s a pressing need to invest more in lower income countries.

Journal: The Lancet Oncology

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