Even what many Americans consider moderate drinking is linked to an increased risk of death, disability, and chronic diseases such as cancer and heart disease, according to a new study in the Journal of Studies on Alcohol and Drugs, published at Rutgers University.

A research team led by Dr. Hyun-Soo Cho at the Stem Cell Convergence Research Center of the Korea Research Institute of Bioscience and Biotechnology (KRIBB), in collaboration with Professor Geun Heo of Kyungpook National University, has identified a key mechanism underlying 5-FU resistance in colorectal cancer and proposed a new therapeutic strategy to restore tumor sensitivity to treatment.

Researchers at Kanazawa University discover how the microenvironment fuels double-negative castration-resistant prostate cancer (DNPC) and demonstrate the therapeutic potential of pan-KRAS inhibitors.

BUFFALO, NY – June 8, 2026 – A new research paper was published in Volume 17 of Oncotarget on June 3, 2026, titled “The anticancer effects of PCAIs in pancreatic cancer cells involve MAPK and PI3K/AKT pathways hyperactivation.”

New funding from CPRIT will help Rice advance cancer research on several fronts, from strengthening a core genetic engineering facility that serves researchers across Texas to supporting new studies in cancer immunotherapy, next-generation radiation therapy and ovarian cancer.

In a step forward for patient-centered cancer research, a new pilot project reveals that 84% of participants had a positive experience using a newly developed online tool created by the Alliance for Clinical Trials in Oncology called the Participant Engagement Portal (PEP). Alliance created PEP to foster direct connection between cancer researchers and the individuals who volunteer for clinical studies. The goal was to make it easier for patients and clinicians to share information, deliver trial updates, and self-report on social risk factors. The results of this national project are published in JNCI Cancer Spectrum.  

New research on older Floridians reveals a striking disparity in melanoma outcomes. Men experience roughly twice as many melanoma-related deaths as women. Non-Hispanic and white populations also face higher rates of melanoma diagnosis and death than Hispanic groups. Researchers suggest differences likely reflect a combination of higher UV exposure, lower sun-protective behaviors and screening in men, disparities in access to care, and possible biological sex differences in immune response. The findings underscore an uneven burden and urgent need for targeted prevention and early detection.

Bladder cancer remains one of the most prevalent urological malignancies worldwide and is frequently associated with high recurrence rates, metastatic progression, and unfavorable long-term clinical outcomes. Although immune checkpoint blockade targeting the PD-1/PD-L1 axis has substantially improved therapeutic management for subsets of patients with advanced bladder cancer, durable clinical responses remain limited because of intrinsic and acquired resistance mechanisms within the tumor microenvironment.