Continuous and fixed-duration treatments result in similar outcomes for CLL
Reports and Proceedings
Updates every hour. Last Updated: 15-Dec-2025 09:11 ET (15-Dec-2025 14:11 GMT/UTC)
According to a new trial, patients with chronic lymphocytic leukemia show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.
In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation. The findings could allow more patients to avoid TBI and its associated long-term side effects.
Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child’s treatment, including losing 25% or more of their household income and struggling to cover the costs of basic living expenses such as housing, food, and utilities.
Poly(N-isopropylacrylamide) (PNIPAM) hydrogel undergoes significant but precise changes in size between 20 and 40 °C, making it an excellent candidate for use in variable-size deterministic lateral displacement (DLD) array devices. Researchers from Science Tokyo have built a tunable DLD cell-sorting platform and verified its ability to sort cancer cells of defined sizes from blood samples. This platform could offer high-resolution size-based cell sorting for a wide variety of biomedical applications
The SECURED project aims at generating libraries and machine learning tools to foster innovation in the fight against blood cancers while preserving the highest privacy standards for sensitive patient data. Dr Eduard Porta, head of the Cancer Immunogenomics team at the Josep Carreras Leukaemia Research Institute is part of this Horizon Europe-funded collaboration that will bring the most sophisticated technologies into the real world.