EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 29-Oct-2026 00:16 ET (29-Oct-2026 04:16 GMT/UTC)

Treatment delays in early age–onset colorectal cancer

JAMA Network
Peer-Reviewed Publication

About The Study: In this cross-sectional study, early age–onset colorectal cancer (EOCRC) was associated with improved overall survival compared with average age–onset colorectal cancer; however, treatment delays were independently associated with worse survival among patients with EOCRC. Language barriers could be a potentially modifiable risk factor associated with delayed treatment and may provide an opportunity to improve timely care and outcomes in EOCRC.

Journal: JAMA Oncology

A blood signature for lung cancer risk: 14 proteins identify people who could benefit from cancer prevention drugs

The Francis Crick Institute
Peer-Reviewed Publication

Researchers at the Francis Crick Institute and University College London (UCL), funded by Cancer Research UK and the European Research Council (ERC), have identified a 14-protein signature in the blood that can predict lung cancer risk more than five years before diagnosis.

Journal: Cell

A single starting point for different cancers

University of Liège
Peer-Reviewed Publication

How do different cancer subtypes arise? Do they originate from distinct cells, or from a single multipotent cell capable of differentiating into multiple cell types? This question, debated for decades in cancer biology, is now gaining new insight thanks to the work of the Laboratory of Experimental Pathology (ULiège), in collaboration with researchers from Université Paris Cité and Sorbonne University.

Journal: Cell Reports

Rare eyelid tumor highlights the importance of accurate diagnosis and pathological evaluation

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY — June 4, 2026 — A new case report was published in Volume 13 of Oncoscience on April 2, 2026, titled “Sebaceous adenoma of the eyelid: A clinical, histopathological, and immunohistochemical perspective.”

Journal: Oncoscience

American Gastroenterological Association’s GI Opportunity Fund backs Amplified Sciences' work to advance pancreatic cyst care

American Gastroenterological Association
Business Announcement

Amplified Sciences, a clinical-stage diagnostics company pioneering next-generation multi-omic assays, today announced a new investment from the American Gastroenterological Association’s (AGA) GI Opportunity Fund as part of its recent Seed+ financing round.

Researchers uncover how aging cells may trigger heart attacks and strokes

University of Texas M. D. Anderson Cancer Center
Peer-Reviewed Publication

Researchers at The University of Texas MD Anderson Cancer Center have discovered a molecular pathway that drives certain stressed or aging cells to become abnormally active, causing inflammation inside blood vessel plaques. This results in disturbed blood flow and high-risk lesions that can lead to blood clots that cause heart attacks or strokes.

Journal: Circulation Research

Notch2 signaling: a key driver of breast cancer dormancy in bone marrow

Editorial Office of West China School of Stomatology, Sichuan University
Peer-Reviewed Publication

Breast cancer can remain dormant in the bone marrow for decades before reactivating, resulting in cancer relapse. A study published in Bone Research unveils the critical role of Notch2 signaling pathway in promoting this dormant state. The study explains how dormant cancer cells mimic healthy stem cells and activate stress pathways to survive in the bone marrow—paving the way for innovative targeted therapies against dormant cancer cells.

Journal: Bone Research

KAIST reveals principle behind ultra-fast DNA repair, like “finding a needle in Seoul"

The Korea Advanced Institute of Science and Technology (KAIST)
Peer-Reviewed Publication

DNA is the blueprint of the human body. However, tens of thousands of DNA lesions occur in our bodies every day. In particular, if “apurinic/apyrimidinic sites” (AP sites, damaged sites where one letter of DNA information has been erased) are not properly repaired, they can lead to cancer and aging. Finding these tiny damaged sites within the vast genome is as difficult as “finding a single needle in Seoul.” Korean researchers have uncovered the secret of how a DNA repair enzyme rapidly searches for damaged sites by sliding along DNA.

Funder: National Research Foundation of Korea, Korea Drug Development Fund, Institute for Basic Science, the Institute of Information & Communications Technology Planning & Evaluatio

A dual metabolic strike: Copper-based nano-PROTACs strengthen cuproptosis cancer therapy

Research
Peer-Reviewed Publication

What happens if cancer cells lose both their mitochondrial energy supply and their glycolytic backup system? This question is central to a new study published in Research by researchers from Northwestern Polytechnical University and collaborating institutions. The work addresses a key limitation of cuproptosis-based cancer therapy: copper-dependent mitochondrial stress can kill cancer cells, but many tumors are metabolically flexible and rely heavily on aerobic glycolysis to survive mitochondrial damage. The study proposes a way to block both routes at once.

Journal: Research
Funder: Shenzhen Science and Technology Program, National Natural Science Foundation of China, Natural Science Basic Research Program of Shaanxi Province, Postdoctoral Research Project of Shaanxi Province, Innovation Capability Support Program of Shaanxi

New CAR T treatment opens doors for patients in need of kidney transplant

University of Pennsylvania School of Medicine
Peer-Reviewed Publication

A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants. These individuals were considered among the most difficult in the nation to match with a compatible donor kidney due to harmful antibodies they had developed (“sensitized”). Researchers at the University of Pennsylvania (Penn) used chimeric antigen receptor (CAR) T-cell therapy, originally developed at Penn for treatment of blood cancer, to significantly reduce the level of harmful immune antibodies in these two highly sensitized patients, making kidney transplantation possible after years of waiting. The study’s findings appear today in the New England Journal of Medicine.

Journal: New England Journal of Medicine