Scientists say they have good news for breast cancer patients, particularly those afflicted with the most aggressive types of the malignant tumor known as triple-negative breast cancer.

A powerful research model developed by MSK researchers clarifies how the most common type of prostate cancer changes into a deadly form.

Hepatocellular carcinoma (HCC) is one of the most fatal malignancies. Epigenetic mechanisms have revealed that noncoding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), are involved in HCC progression. This study aimed to construct a circRNA-miRNA-mRNA network in HCC and validate one axis within the network.

Mesothelioma is an aggressive tumor with a poor prognosis. Histological diagnosis of mesothelioma using limited tissue samples can be challenging. Carbonic anhydrase IX (CAIX) is a transmembrane protein that is overexpressed in a variety of solid tumors. This study aimed to investigate the clinical utility of CAIX expression in the differential diagnosis of pleural mesothelioma from non-small cell lung carcinoma (NSCLC).

A comprehensive new 10-year study led by researchers at Arizona State University examined more than 16,000 necropsy records from 292 vertebrate species, revealing significant differences in the prevalence of cancer. The findings offer new insights into cancer evolution while challenging Peto’s paradox — a key concept in evolutionary biology.