Today, the American Association for Cancer Research (AACR) released the 15th edition of its annual Cancer Progress Report. A cornerstone of the AACR’s educational and advocacy efforts, this comprehensive report provides the latest statistics on cancer incidence, mortality, and survivorship and highlights how federal investments in basic, translational, and clinical cancer research and cancer-related population sciences have led to impressive scientific advances that are improving health and saving lives.

New research has shown why preserving lymph nodes, often removed near tumours to prevent cancer spread, could improve patient outcomes and make immunotherapies more effective.

A bout of the common bladder infection, cystitis, may signal the presence of urogenital cancers—which affect parts of the body involved in reproduction and excretion—in middle aged adults, suggests research published in the open access journal BMJ Public Health. 

The Alliance for Clinical Trials in Oncology will host a public webinar on Monday, September 29, at 12 pm CT showcasing the key findings of Alliance research presented at the 2025 American Society for Clinical Oncology (ASCO) Annual Meeting. The clinical trial results discussed at the virtual meeting will include some of the latest information for people living with colorectal, squamous cell, and renal cell cancers.  

Sutter Health researchers at California Pacific Medical Center have identified a promising new drug combination that may help patients with advanced melanoma whose cancer no longer responds to immunotherapy. In preclinical models, the regimen both shrank tumors and reactivated the immune system, offering hope for new treatment strategies. A clinical trial testing this approach is expected to begin at Sutter by late 2025.

A new UCLA-led study has found that a surgical technique developed to protect vision in patients with uveal melanoma, a rare cancer that arises inside the eye, may also lower the risk of the disease spreading and improve survival — a development researchers say could change the way the cancer is treated. 

Three leading national cancer organizations today issued an updated guideline on post-mastectomy radiation therapy (PMRT) for physicians treating patients with breast cancer. The American Society for Radiation Oncology (ASTRO), the American Society of Clinical Oncology (ASCO) and the Society of Surgical Oncology (SSO) issued recommendations that outline when PMRT is appropriate based on new evidence and evolving clinical practice, and highlight best practices for delivering radiation after breast removal surgery in a multidisciplinary, patient-centered setting.