American Gastroenterological Association’s GI Opportunity Fund backs Amplified Sciences' work to advance pancreatic cyst care
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Updates every hour. Last Updated: 24-Jun-2026 08:15 ET (24-Jun-2026 12:15 GMT/UTC)
Researchers at The University of Texas MD Anderson Cancer Center have discovered a molecular pathway that drives certain stressed or aging cells to become abnormally active, causing inflammation inside blood vessel plaques. This results in disturbed blood flow and high-risk lesions that can lead to blood clots that cause heart attacks or strokes.
Breast cancer can remain dormant in the bone marrow for decades before reactivating, resulting in cancer relapse. A study published in Bone Research unveils the critical role of Notch2 signaling pathway in promoting this dormant state. The study explains how dormant cancer cells mimic healthy stem cells and activate stress pathways to survive in the bone marrow—paving the way for innovative targeted therapies against dormant cancer cells.
The ASCERTAIN V clinical trial demonstrated that an all-oral drug combination for older patients with acute myeloid leukemia (AML) is an effective alternative to the current standard, which requires repeated hospital or office visits for intravenous treatment. In the international phase 1/phase 2 trial led by researchers at Weill Cornell Medicine, NewYork-Presbyterian, Yale University and MD Anderson Cancer Center, patients took a regimen of two pills, decitabine-cedazuridine and venetoclax, with strong response rates and survival outcomes.