Breast cancer remodels lymphatic vessels to accelerate its spreading
Peer-Reviewed Publication
Updates every hour. Last Updated: 16-Dec-2025 14:11 ET (16-Dec-2025 19:11 GMT/UTC)
Breast cancer is able to modify the lymphatic vessels through which it travels to the draining lymph nodes. From there, it can then spread to other parts of the body. A new finding by Finnish researchers may help develop targeted therapies that could prevent this spread.
For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an emergency room visit. Such visits can be financially costly and take an emotional toll on patients and their caregivers. A new study led by Mayo Clinic researchers found that using digital check-ins and a remote care team can help patients manage symptoms before they reach a crisis point.
Researchers examined five AI models on multiple genomic tasks to see how well they performed
Models performed well overall, with each having strengths and weaknesses based on the desired task
Study provides a framework for researchers to choose optimal AI models for specific genomic tasks
Researchers from Mass General Brigham Cancer Institute will present research discoveries and outcomes from clinical trials in hematology/oncology, including cancer and common blood disorders, at the 2025 American Society of Hematology (ASH) annual meeting, held December 6-9, in Orlando.
A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in post-menopausal women with obesity. It also raises the possibility that treatment of these aggressive breast cancers could be improved with addition of weight-loss drugs known as GLP-1 receptor agonists.
Cambridge, MA — 12/02/2025 — Insilico Medicine (“Insilico”), a global leader in AI-powered drug discovery, and Atossa Therapeutics (“Atossa”) (Nasdaq: ATOS), a clinical-stage biopharmaceutical company developing novel treatments for breast cancer and other serious conditions, announce the publication of a joint study evaluating the potential of (Z)-endoxifen for glioblastoma multiforme (GBM). The peer-reviewed article, now published in Nature’s Scientific Reports, represents one of the most comprehensive AI-enabled analyses to date exploring whether endoxifen, an active metabolite of tamoxifen with known activity in endocrine-resistant breast cancer, may offer new therapeutic opportunities for one of the deadliest malignant brain tumors in adults. The study aimed to identify new oncology indications with high therapeutic potential for endoxifen, as monotherapy or in combination, by applying Insilico’s AI-powered PandaOmics platform across a wide range of cancer types based on its mechanisms of action. Through this systematic evaluation, GBM emerged as a top candidate for further investigation.