Fovinaciclib for first-line therapy of advanced breast cancer
Peer-Reviewed Publication
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A recent review provides an overview of the purinergic receptor P2Y2 and its involvement in cancer-related processes. The article discusses how extracellular nucleotide signaling may influence tumor cell behavior and the tumor microenvironment, and evaluates the potential of P2Y2 as a biomarker and therapeutic target.
Colorectal cancer is the second leading cause of death from cancer in the United States. Recent research pointed to stem cells as a significant primary driver of colorectal cancer, but exactly what happens at the cellular level inside the gut is less clear. A new study by researchers at Stevens Institute of Technology sheds, outlines a mechanism by which colorectal cancers can evolve from mature intestinal cells that revert to stem cells and suggests pathways for effective therapies.