Novel tool helps identify key targets to strengthen CAR NK cell therapies
Peer-Reviewed Publication
Updates every hour. Last Updated: 10-Sep-2025 15:11 ET (10-Sep-2025 19:11 GMT/UTC)
Natural killer (NK) cells became markedly better at killing cancer cells after scientists removed key gene targets identified through a new genome-wide CRISPR screening tool, according to new research from The University of Texas MD Anderson Cancer Center.
The National Cancer Institute of the National Institutes of Health has awarded Dr. Anna Gottschlich, assistant professor of oncology in the Wayne State University School of Medicine and the Barbara Ann Karmanos Cancer Institute’s Population Studies and Disparities Research Program, a five-year, $916,545 career development award to support her research on the epidemiology of cancer health disparities and early detection and interception strategies to improve cancer equity.
Researchers at Beijing Tiantan Hospital have developed a one-stage hybrid approach that combines embolization and microsurgical removal of hypervascular central nervous system (CNS) tumors in a single operation. In a decade-long study of 31 patients, this innovative method reduced blood loss, avoided embolization-related complications, and preserved neurological function. Published in the Chinese Neurosurgical Journal, the findings suggest a safer alternative to traditional staged surgeries for treating high-risk brain and spinal tumors.