Cervical cancer will be the first human cancer eliminated through coordinated global action.

Women living close to federally designated Superfund sites are more likely to develop aggressive breast cancers — including the hard-to-treat triple-negative subtype — according to new studies from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

The aim of immunotherapy strategies is to leverage cells in the patient's own immune system to destroy tumor cells. Using a preclinical model, scientists from the Institut Pasteur and Inserm successfully stimulated an effective anti-tumor immune response by reprogramming the death of malignant B cells. They demonstrated an effective triple-therapy approach for treating forms of blood cancer such as certain lymphomas and leukemias which affect B cells. The study was published on August 15 in the journal Science Advances.

Scientists have developed a highly sensitive single-cell tool that can help uncover links to complex diseases. Known as single-cell DNA-RNA-sequencing (SDR-seq), this tool created by scientists from EMBL's Genome Biology Unit can study both DNA and RNA simultaneously inside the same cell – a critical element in understanding how genetic variants impact gene expression in what’s called the non-coding region of the genome.

With SDR-seq, the scientists found that even small changes in DNA can change how genes are regulated in stem cells, and in a type of blood cancer called B-cell lymphoma.   

SDR-seq offers genome biologists scale, precision, and speed to help understand and eventually treat a broad range of diseases.