New clinical trial to target cancer’s elusive growth switch
Peer-Reviewed Publication
Updates every hour. Last Updated: 10-Nov-2025 09:11 ET (10-Nov-2025 14:11 GMT/UTC)
Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key pathway for tumour growth.
Now entering the first clinical trial in humans, if found to be safe and effective, these drugs could be used to treat many different types of cancers while avoiding effects on healthy cells.
The Genetic Wellness Assessment allows individuals to determine whether they may have a higher genetic risk of developing cancer by answering a few simple questions that evaluate individual risk factors. Those identified as having a high risk, or anyone interested in further evaluation, can schedule an appointment to discuss genetic testing. The results of genetic testing are used by healthcare providers to offer personalized recommendations for cancer screening, prevention and further evaluation for patients and family members.
AMHERST, Mass. — A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice. Not only did up to 88% of the vaccinated mice remain tumor-free (depending on the cancer), but the vaccine reduced—and in some cases completely prevented—the cancer’s spread.
In its mission to accelerate transformative cancer innovations and drive cures forward, the AIM-HI Accelerator Fund is pleased to announce the winners of the 2025 AIM-HI Venture Competition: ResNovas Therapeutics, co-founded by Nobel Laureate Carolyn Bertozzi, Ph.D., Michelle Arkin, Ph.D., CTO Ian Churcher, Ph.D., and CEO Gabriele Sulli, Ph.D.; and Chiara Biosciences, co-founded by National Academy of Inventors Fellow Francis Barany, Ph.D. and CEO Kirsten Flowers, MBA.
A smoking cessation program developed by WashU Medicine researchers and deployed at Siteman Cancer Center prolongs life for cancer patients, according to a new study. Regardless of their type of cancer or how advanced it was, cancer patients lived nearly a year longer when they quit smoking compared to patients who continued smoking.
Australia needs to be innovative when it comes to skin cancer detection by embracing a nurse-led model that could save thousands of lives in the long run, according to a new paper.