Scientists discovered that three TCF7-expressing tumor-reactive T cell subpopulations exhibit selective expansion during ovarian tumor-infiltrating T cell production ex vivo. CD8⁺ TCF7⁺ Tpex cells demonstrate self-renewal capacity and generate stem-like progenies. CD8⁺ TCF7⁺ Tpex and CD4⁺ TCF7⁺ Tfh cells are both marked by the co-expression of CCR7 and CD200. Selectively expanding CCR7⁺CD200⁺ T cells enriches stem-like, tumor-reactive T cells, enabling precise ex vivo expansion of therapeutic T cell subpopulations for adoptive cell therapy.

The introduction of artificial intelligence (AI) to assist colonoscopies is linked to a reduction in the ability of endoscopists (health professionals who perform colonoscopies) to detect precancerous growths (adenomas) in the colon without AI assistance, according to a paper published in The Lancet Gastroenterology & Hepatology journal. 

Ali Weinstein, professor of global and community health and senior scholar at the Center for the Advancement of Well-Being studied how breast cancer survivors respond to physically and mentally tiring tasks. Researchers measured changes in both inflammation and participants’ self-reported fatigue, two common symptoms among breast cancer survivors that are believed to be connected, impact quality of life, and may also play a role in cancer recurrence.  

The American Cancer Society (ACS) has awarded The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai a $4.08 million grant to establish the Cancer Health Research Center at Mount Sinai, a new initiative dedicated to reducing cancer-related health inequities across New York City.

The Pew Charitable Trusts and the Alexander and Margaret Stewart Trust announced the 2025 class of the Pew-Stewart Scholars Program for Cancer Research.

The Pew Charitable Trusts announced the 2025 class of the Pew Latin American Fellows Program in the Biomedical Sciences.

In a recently published study, researchers at Fox Chase Cancer Center revealed for the first time that cancer cells can evade anti-cancer drugs by entering and surviving within bone marrow fibroblasts, a phenomenon they describe as “cell-in-cell.”

Up slightly from 16% last year, only 19% of women say a health care provider has discussed with them nutrition’s role in breast cancer risk in a new Physicians Committee for Responsible Medicine/Morning Consult survey. However, fewer of those same women specifically mention diet this year when asked what steps they’re aware of that women can take to lower their chances of developing breast cancer.