Embargoed study: Breaking the link between alcohol use and pancreatic cancer
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Updates every hour. Last Updated: 11-Sep-2025 06:11 ET (11-Sep-2025 10:11 GMT/UTC)
Gastric cancer that metastasizes to the peritoneum, or the lining of the abdominal cavity, has a very poor prognosis and is challenging to treat. Now, a group of researchers has developed mRNA-based vaccines that can target tumor-specific ‘neoantigens.’ In combination with anti-PD1 therapy, these vaccines show high antitumor efficacy against gastric cancer with peritoneal metastasis. This approach can potentially be expanded in order to develop ‘personalized’ cancer vaccines for complicated cancer cases.
Inhibiting a specific gene, MET, in combination with standard chemotherapy and immunotherapy, enhances treatment efficacy and limits tumor growth in small cell lung cancer (SCLC). The study, led by the Hospital del Mar Research Institute, analyzed the effect of MET inhibition in mouse models and studied gene expression in patient tumor samples. The results are published in Cell Reports Medicine. Researchers aim to pursue this line of research with a clinical trial involving patients.
Scientists at Tsinghua University have developed a method to grow kidney tumours in the lab using cells from real patients, offering a potential new tool in the fight against renal cancer. Their research, published in the journal Biofabrication, outlines how 3D bioprinting technology can be used to replicate the unique characteristics of each patient’s tumour.
Researchers at City of Hope published a new study which found that some survivors of childhood cancer are more at risk for serious health issues as they grow older, including new cancers and chronic conditions like heart disease.