Cancer cells survive by repairing damage to their DNA—even damage that would normally be fatal. One of their most important defense systems is homologous recombination, a high-precision repair pathway that fixes broken DNA using key proteins such as RAD51 and CHK1. While therapies such as PARP inhibitors have successfully targeted this vulnerability, many tumors eventually regain their DNA repair ability and become resistant to treatment.

A research team led by Director MYUNG Kyungjae at the Center for Genomic Integrity within the Institute for Basic Science (IBS), in collaboration with LEE Joo-Yong (Chungnam University) has now uncovered a new strategy to overcome this resistance. Their findings show that cancer cells can be made vulnerable again—not by altering genetic mutations, but by destabilizing the DNA repair machinery itself.

The University of Texas MD Anderson Cancer Center today announced the appointment of Kim Slusser, Ph.D., R.N., as the institution’s inaugural chief nurse executive (CNE), effective May 1.

Tiny flexible lasers can be used to measure forces inside living cells, which could help illuminate various biological processes, including those involved in early development and tumor progression.

Researchers from QST, The University of Tokyo, and Kyushu University have developed biocompatible molecular quantum nanosensors (MoQNs) that function inside living cells. These sensors enable precise, absolute temperature measurements at subcellular resolution and detect radical-related spin signals in both cytoplasm and nucleus. By using molecular spin qubits in nanocrystals, MoQNs overcome limitations of existing sensors, offering improved uniformity, stability, and biocompatibility, opening new possibilities for intracellular thermometry and biochemical sensing. 

BUFFALO, NY – April 29, 2026 – A new research paper was published in Volume 17 of Oncotarget on April 28, 2026, titled “Targeted therapeutics and U.S. population-level mortality trends in multiple myeloma: A SEER-based analysis from 1975 to 2023.”