Ferrocene-modified nanoscale covalent organic frameworks for ferroptosis-based sonodynamic therapy inhibit breast cancer and its bone metastasis
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Jun-2026 21:16 ET (22-Jun-2026 01:16 GMT/UTC)
A research paper by scientists at Gongli Hospital of Pudong New Area presented developed a sonodynamic nanoplatform that simultaneously eradicates primary breast tumors via ferroptosis and apoptosis and blocks their spread to bone tissues.
The research paper, published on Mar 23, 2026 in the journal Cyborg and Bionic Systems.
Colorectal cancer often returns not because the main tumor survives, but because a small population of stem-like cancer cells can resist treatment, seed new growth, and drive aggressive spread.
A global review of liver cancer trends using GLOBOCAN 2022 and Global Burden of Disease data reveals a shift from viral hepatitis to metabolic disease as a leading cause. While incidence and mortality remain high, particularly in China, improved vaccination and treatment have reduced virus-related cases. Rising obesity and lifestyle risks now drive new cases. The study highlights prevention, early detection, and AI-driven care as critical strategies to curb future liver cancer burden worldwide.
At present, only around 5% of patients with colon cancer are candidates for immunotherapy. This new biomarker could make it possible to determine more accurately which individuals may receive this treatment with a likelihood of success and expand the number of patients who could benefit from it. The study, led by the Hospital del Mar Research Institute and IRB Barcelona, shows that the determination of this protein, CTHRC1, can be used to assess patient prognosis. At the same time, it opens up new avenues to approach this type of tumour. The research team has demonstrated that this biomarker can be detected using routine diagnostic tests in the clinical practice of any Pathology service.