EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 27-Oct-2026 09:16 ET (27-Oct-2026 13:16 GMT/UTC)

Preoperative high-dose corticosteroids in digestive cancer surgery

JAMA Network
Peer-Reviewed Publication

About the Study: In this randomized clinical trial of elective digestive cancer surgery, a preoperative pulse dose of methylprednisolone did not improve major postoperative outcomes compared with placebo. The findings do not support routine use of high-dose corticosteroids in this setting.

Journal: JAMA Surgery

Bacteria found in lung tumors may boost immune response to cancer

Johns Hopkins Medicine
Peer-Reviewed Publication

Bacteria in lung tumors may boost the activation of innate immune cells in the presence of a common vitamin metabolite, according to a preclinical study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

Journal: Proceedings of the National Academy of Sciences
Funder: Commonwealth Foundation, Bloomberg~Kimmel Institute for Cancer Immunotherapy

Hidden drivers of aggressive childhood cancer revealed

Wellcome Trust Sanger Institute
Peer-Reviewed Publication

New clues have been uncovered about why the childhood cancer, rhabdomyosarcoma, may unexpectedly behave aggressively.

Journal: Cancer Research

Cell-preservation technique could make CAR-T cell therapy more accessible

Massachusetts Institute of Technology
Peer-Reviewed Publication

MIT researchers developed a way to protect CAR-T cells from damage that can occur when they are frozen for storage and shipment. Their technique should make it easier for more hospitals to provide this treatment option to cancer patients.

Journal: Trends in Biotechnology
Funder: Ludwig Center at MIT’s Koch Institute, Convergence Scholars Program, MIT Marble Center for Cancer Nanomedicine

Colon cancer: How highly aggressive tumors evade the immune system

German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)
Peer-Reviewed Publication

Researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have identified a previously unknown mechanism by which a particularly aggressive form of colon cancer evades the immune system. The findings show that the activation of a key signaling pathway helps cancer cells suppress the immune system, thereby promoting the development of malignant tumors.

Journal: Gastroenterology

Aging reprograms skin genetic activity and promotes inflammation

Institute for Research in Biomedicine (IRB Barcelona)
Peer-Reviewed Publication

Researchers at IRB Barcelona identify a molecular mechanism that amplifies chronic inflammation in aged skin.

With age, two proteins that normally help maintain epidermal function, BMAL1 and YAP, switch to promoting genes associated with inflammation.

The study, conducted mainly in mice and supported by the analysis of human skin data, has been published in the journal Nature Aging.

Journal: Nature Aging

Can antioxidant foods help prevent cervical cancer?

Wiley
Peer-Reviewed Publication

In research published in the International Journal of Gynecology & Obstetrics, a diet high in antioxidants was linked with a lower risk of cervical cancer in women.

Journal: International Journal of Gynecology & Obstetrics

Charles W.M. Roberts, MD, PhD, an internationally recognized physician-scientist, named president and CEO of St. Jude Children’s Research Hospital

St. Jude Children's Research Hospital
Business Announcement

Roberts has fostered collaborative, innovative partnerships across disciplines and institutions to accelerate progress against childhood cancer and other catastrophic diseases.

Lifesaving cancer treatment without life-threatening side effects

University of California - Irvine
Peer-Reviewed Publication

UC Irvine researchers highlight mitochondrial dysfunction as a promising target for reducing a serious neurological complication of CAR T-cell therapy in cancer patients.

The study outlines how existing drugs could be repurposed as safer alternatives to steroids in addressing this complication.

The research provides a road map for future clinical evaluation.

Journal: Frontiers in Pharmacology

T cells ditch exhaustion marker to escape tumors and protect against cancer relapse

University of Pittsburgh
Peer-Reviewed Publication

As the immune system battles cancer, chronic stimulation gradually drives T cells to a state of exhaustion. But some of these exhausted T cells can lose expression of the exhaustion marker LAG3, move out of the tumor, and confer long-lasting immunity to cancer in mice.

Journal: Journal of Experimental Medicine
Funder: Parker Institute for Cancer Immunotherapy

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