Malignancy Spectrum, a cutting-edge journal dedicated to advancing the field of oncology, presents its latest issue, Volume 1, Issue 4.

This issue delves into the complex and multifaceted nature of cancer, offering a comprehensive exploration of the latest research, clinical findings, and innovative treatments. From the molecular underpinnings of tumor development to the latest breakthroughs in targeted therapies, this issue provides a platform for researchers, clinicians, and scientists to share their insights and discoveries. With a focus on basic and translational research, Malignancy Spectrum aims to bridge the gap between laboratory findings and clinical practice, ultimately improving patient outcomes and quality of life.

The research team of Wang Jianli of the Chun Institute of Optics, President of the Chinese Academy of Sciences, has made progress in the observation of space objects based on metalens. In this study, the 2D concentric-ring structure, which is easier to process, is used as the basic configuration of the metalens, and the 2D meta-atoms are designed to be compatible with transverse electromagnetic wave and Transverse magnetic wave modes .Therefore, a portable telescopic system with a concentric-ring metalens with a diameter of 5cm as the main lens was developed, which achieve high-resolution detection within a 20° field of view, and further advances the deep application of metalens in the field of astronomical observation.

The continued intensification of global warming has made extreme heat events an increasingly severe threat to crop production. Cotton, as a globally important economic crop and a strategic pillar of China’s textile industry, faces significant challenges from frequent extreme high-temperature events during the summer. The high overlap between extreme heat and the blooming and boll-setting stages of cotton leads to issues such as pollen inactivation, anther non-dehiscence, and bud and boll shedding, severely affecting cotton yield and quality. This has become a critical bottleneck restricting the high-quality development of the cotton industry. Therefore, breeding heat-tolerant cotton capable of withstanding high-temperature stress has become an urgent need in the field of crop breeding.

Incorporating trace amounts of Cu atoms into n-type Bi₂(Te, Se)₃ simultaneously realizes lattice plainification and band structure engineering, thus substantially facilitating thermoelectric transport and leading to excellent device efficiencies.

Researchers have experimentally demonstrated a groundbreaking quantum imaging method using ultra-thin nonlinear metasurfaces. The study predicts unprecedented resolution and field of view by combining ghost imaging and all-optical scanning techniques, outperforming conventional bulky systems. This innovation has transformative potential for quantum sensing, imaging, and communications technologies.

In a landmark discovery, researchers applied a novel AI model called the max-logistic intelligence classifier to analyze 865,859 CpG methylation sites in early COVID-19 patients' blood samples. They uncovered compelling evidence that COVID-19 most likely originated from the natural synthesis of two rare but serious infectious diseases, glanders and Sennetsu fever, with some common human diseases.