Refining epilepsy surgery: A large-scale study reveals how SEEG improves decision-making in temporal lobe epilepsy
Peer-Reviewed Publication
Updates every hour. Last Updated: 4-Nov-2025 15:11 ET (4-Nov-2025 20:11 GMT/UTC)
A research team from Beijing Tiantan Hospital has conducted the largest clinical investigation to date into the use of stereoelectroencephalography (SEEG) in temporal lobe epilepsy (TLE). Based on a surgical cohort of 695 patient, including 192 who underwent SEEG monitoring, the study provides comprehensive insights into how SEEG contributes to surgical decision-making, identifies predictors of seizure outcomes, and informs treatment strategies for complex epilepsy cases. The findings have been published in the journal Science Bulletin.
Researchers generated the most comprehensive single-nucleus transcriptomic atlas of pig intestines to date, covering wild boars and domestic pigs across four key postnatal developmental stages. The study identified 19 major cell types and 58 cellular subtypes, revealed unique neuronal regulation of intestinal inflammatory response in the ileum, and showed why wild boars exhibit stronger immune responses and nutrient absorption than domestic pigs. These findings provide new insights into improving pig feed efficiency and health, while offering valuable references for human intestinal disease research.
High-temperature superconductivity has long been hailed as the “crown jewel” of condensed matter physics. In 2023, the nickel-based compound La3Ni2O7 was found to exhibit superconductivity above 80 K under high pressure, setting a new record for nickelates and opening a fresh platform to explore high-Tc mechanisms. Professors Kun Jiang (Institute of Physics, CAS) and Fu-Chun Zhang (Kavli Institute for Theoretical Sciences, UCAS) and their team proposed that La3Ni2O7 can be described as a “self-doped molecular Mott insulator,” where strong correlations and interlayer coupling drive superconductivity in a way reminiscent of cuprates. This work provides new insights into the origin of high-temperature superconductivity.
Lithium–sulfur (Li–S) batteries require efficient catalysts to accelerate polysulfide conversion and mitigate the shuttle effect. However, the rational design of catalysts remains challenging due to the lack of a systematic strategy that rationally optimizes electronic structures and mesoscale transport properties. In this work, we propose an autogenously transformed CoWO4/WO2 heterojunction catalyst, integrating a strong polysulfide-adsorbing intercalation catalyst with a metallic-phase promoter for enhanced activity. CoWO4 effectively captures polysulfides, while the CoWO4/WO2 interface facilitates their S–S bond activation on heterogenous catalytic sites. Benefiting from its directional intercalation channels, CoWO4 not only serves as a dynamic Li-ion reservoir but also provides continuous and direct pathways for rapid Li-ion transport. Such synergistic interactions across the heterojunction interfaces enhance the catalytic activity of the composite. As a result, the CoWO4/WO2 heterostructure demonstrates significantly enhanced catalytic performance, delivering a high capacity of 1262 mAh g−1 at 0.1 C. Furthermore, its rate capability and high sulfur loading performance are markedly improved, surpassing the limitations of its single-component counterparts. This study provides new insights into the catalytic mechanisms governing Li–S chemistry and offers a promising strategy for the rational design of high-performance Li–S battery catalysts.
Long-life energy storage batteries are integral to energy storage systems and electric vehicles, with lithium-ion batteries (LIBs) currently being the preferred option for extended usage-life energy storage. To further extend the life span of LIBs, it is essential to intensify investments in battery design, manufacturing processes, and the advancement of ancillary materials. The pursuit of long durability introduces new challenges for battery energy density. The advent of electrode material offers effective support in enhancing the battery's long-duration performance. Often underestimated as part of the cathode composition, the binder plays a pivotal role in the longevity and electrochemical performance of the electrode. Maintaining the mechanical integrity of the electrode through judicious binder design is a fundamental requirement for achieving consistent long-life cycles and high energy density. This paper primarily concentrates on the commonly employed cathode systems in lithium-ion batteries, elucidates the significance of binders for both, discusses the application status, strengths, and weaknesses of novel binders, and ultimately puts forth corresponding optimization strategies. It underscores the critical function of binders in enhancing battery performance and advancing the sustainable development of lithium-ion batteries, aiming to offer fresh insights and perspectives for the design of high-performance LIBs.
Crystalline silicon (c-Si) solar cells, though dominating the photovoltaic market, are nearing their theoretical power conversion efficiencies (PCE) limit of 29.4%, necessitating the adoption of multi-junction technology to achieve higher performance. Among these, perovskite-on-silicon-based multi-junction solar cells have emerged as a promising alternative, where the perovskite offering tunable bandgaps, superior optoelectronic properties, and cost-effective manufacturing. Recent announced double-junction solar cells (PSDJSCs) have achieved the PCE of 34.85%, surpassing all other double-junction technologies. Encouragingly, the rapid advancements in PSDJSCs have spurred increased research interest in perovskite/perovskite/silicon triple-junction solar cells (PSTJSCs) in 2024. This triple-junction solar cell configuration demonstrates immense potential due to their optimum balance between achieving a high PCE limit and managing device complexity. This review provides a comprehensive analysis of PSTJSCs, covering fundamental principles, and technological milestones. Current challenges, including current mismatch, open-circuit voltage deficits, phase segregation, and stability issues, and their corresponding strategies are also discussed, alongside future directions to achieve long-term stability and high PCE. This work aims to advance the understanding of the development in PSTJSCs, paving the way for their practical implementation.
Researchers provide a near-complete genome map of Northern wild rice, uncovering evolutionary history and valuable genetic insights
Aqueous Zn-iodine batteries (ZIBs) face the formidable challenges towards practical implementation, including metal corrosion and rampant dendrite growth on the Zn anode side, and shuttle effect of polyiodide species from the cathode side. These challenges lead to poor cycle stability and severe self-discharge. From the fabrication and cost point of view, it is technologically more viable to deploy electrolyte engineering than electrode protection strategies. More importantly, a synchronous method for modulation of both cathode and anode is pivotal, which has been often neglected in prior studies. In this work, cationic poly(allylamine hydrochloride) (Pah+) is adopted as a low-cost dual-function electrolyte additive for ZIBs. We elaborate the synchronous effect by Pah+ in stabilizing Zn anode and immobilizing polyiodide anions. The fabricated Zn-iodine coin cell with Pah+ (ZnI2 loading: 25 mg cm−2) stably cycles 1000 times at 1 C, and a single-layered 3 × 4 cm2 pouch cell (N/P ratio ~ 1.5) with the same mass loading cycles over 300 times with insignificant capacity decay.
The advancement of flexible memristors has significantly promoted the development of wearable electronic for emerging neuromorphic computing applications. Inspired by in-memory computing architecture of human brain, flexible memristors exhibit great application potential in emulating artificial synapses for high-efficiency and low power consumption neuromorphic computing. This paper provides comprehensive overview of flexible memristors from perspectives of development history, material system, device structure, mechanical deformation method, device performance analysis, stress simulation during deformation, and neuromorphic computing applications. The recent advances in flexible electronics are summarized, including single device, device array and integration. The challenges and future perspectives of flexible memristor for neuromorphic computing are discussed deeply, paving the way for constructing wearable smart electronics and applications in large-scale neuromorphic computing and high-order intelligent robotics.
Without early detection, conditions such as congenital heart defects and familial hypercholesterolemia (FH) can quietly disrupt growth, energy levels, and long-term organ function.
Whole Genome Sequencing (WGS) can detect these risks at the earliest possible stage. It shifts cardiac care away from crisis management toward proactive, precision prevention.