Assembly of 2D organic crystals into vertical heterostructures for tunable light emission
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Oct-2026 18:16 ET (23-Oct-2026 22:16 GMT/UTC)
The WHO Global Action Plan for Poliovirus Containment, 4th edition (GAPIV) describes the necessary conditions for the containment of poliovirus material in poliovirus-essential facilities (PEFs). The method used for validation of chemical products for poliovirus decontamination in this study was based on processes outlined in European Standard EN14476, as recommended by the WHO GAPIV guidelines. The disinfectants 5 % Microchem Plus and 1 % Virkon®S were evaluated for efficacy against high titre poliovirus in solutions with and without high organic load using an endpoint dilution assay. A poliovirus Sabin 1 strain was used as the reference virus with the titre 8.33 log10 CCID50 (50 % cell culture infectious dose) in 0.1 ml. Microchem Plus only partially inactivated poliovirus and cannot be relied upon as the sole decontaminant. In contrast, Virkon®S performed well for both high titre poliovirus in solutions with and without high organic load, achieving >4 log10 titre reduction for both, making Virkon®S a suitable disinfectant for poliovirus.
Using seawater for large-scale electrolysis offers a highly promising route for sustainable energy systems, but aggressive chloride ions typically cause rapid degradation of conventional anodic catalysts. Researchers from Hainan University and Swinburne University of Technology have developed a self-stabilizing boron-doped high-entropy selenide for the anodic oxygen evolution reaction. By coupling dynamic valence oscillations for active-site protection with a robust selenate layer to repel chloride, this catalyst achieves over 1000 hours of continuous operation at industrial-level currents in a harsh seawater environment.
Researchers have developed an injectable supramolecular carrier that co‑encapsulates two hydrophobic anti‑inflammatory drugs within a hyaluronic acid matrix via Schiff‑base chemistry. The system achieves pH‑responsive release, suppresses inflammatory cytokines, promotes cartilage repair in a rat osteoarthritis model, and avoids the systemic toxicity of oral medications.
In vivo immune cell engineering directly reprograms endogenous immune cells, bypassing individualized ex vivo manufacturing and opening a path toward more accessible and scalable cell therapies. This review summarizes cell-specific engineering strategies, compares viral and non-viral delivery platforms, highlights emerging applications in cancer, autoimmune and degenerative diseases, and discusses the key challenges that must be overcome for clinical translation.
Researchers have developed an injectable supramolecular carrier that co‑encapsulates two hydrophobic anti‑inflammatory drugs within a hyaluronic acid matrix via Schiff‑base chemistry. The system achieves pH‑responsive release, suppresses inflammatory cytokines, promotes cartilage repair in a rat osteoarthritis model, and avoids the systemic toxicity of oral medications.