An epidemiologically validated spatial modeling approach enables mapping seamless, fine-scale heat-related health risks
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Oct-2026 01:15 ET (26-Oct-2026 05:15 GMT/UTC)
This study develops a novel “Panning for Gold” framework that integrates Koopman analysis with clustering algorithms to identify representative water quality dynamic data for wastewater treatment plants (WWTPs). Using a full-scale Anaerobic-Anoxic-Oxic process in southern China as a case study, the research demonstrates that machine learning models can maintain predictive accuracy with 43.59% less training data, establishing a low-data-requirement paradigm for efficient water system management.
Researchers developed a palladium-engineered nickel phosphide catalyst for selective bio-oil upgrading. In anisole tests at 200 ℃, NiPdP achieved near-complete conversion and 97.28% selectivity to cyclohexane; with m-cresol at 250 ℃, selectivity to methylcyclohexane reached 95.72%. Palladium altered catalyst formation, lattice strain and electronic structure, helping suppress unwanted carbon–carbon bond cleavage, sintering and coke formation while supporting reuse over 10 cycles.
The present study investigated the disease burden and associated productivity losses attributable to T2DM among adults, while also forecasting the disease burden through 2050. The study adopted a quantitative approach and drew upon datasets obtained from the Global Burden of Disease (GBD) 2021 database, the World Bank, the United Nations, and the International Labor Organization. Projections based on the BAPC model indicate that the ASDR will rise to 2243.12 per 100,000 population by 2050. The estimated annual productivity loss attributable to T2DM in the region exceeds 220 billion U.S. dollar (USD). Comprehensive and sustainable interventions, including health policies, educational initiatives, and social protection measures, are needed to reduce disparities associated with T2DM.
We are pleased to present a curated collection of our recent cover articles, featuring breakthroughs ranging from enzyme–chemical interaction prediction, genome-scale modeling and novel biosensor development to metabolic engineering of industrially relevant microbial hosts and next-generation gene-editing tools. These studies highlight the field's rapid evolution from fundamental tool discovery to translational industrial applications.
Published chemical literature has accumulated a wealth of reaction data, but this data comes from diverse sources, is unevenly distributed, and is clearly biased towards highly selective "successful experiments." Can such literature data be used for reliable machine learning modeling and further guide new catalytic reactions? Professor Luo Sanzhong's team and collaborators at Tsinghua University recently reported OrgAIcat, a machine learning framework for asymmetric organocatalysis. The research team manually compiled over 22,000 data points on Aldol and Michael addition reactions from 844 papers to construct the iSynth dataset. Based on this, the team developed R-SPOC, a reaction descriptor that requires no quantum chemical calculations, for predicting enantioselectivity and screening catalysts. When OrgAIcat was combined with Bayesian optimization, a challenging Aldol reaction was improved from 41% ee to 96% ee, with the entire optimization process requiring only 12 experiments. These results demonstrate that after rigorous compilation, proper characterization, and sufficient validation, historical literature data can still be used to guide experiments, despite its heterogeneity and publication bias. The article was published as an open access Research Article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.