EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 15-Jul-2025 17:11 ET (15-Jul-2025 21:11 GMT/UTC)

13-Mar-2025

Faeth Therapeutics and The Gog Foundation, Inc. (GOG-F) launch first phase 2 combination trial for sapanisertib-serabelisib in patients with endometrial cancer

The GOG Foundation Inc
Business Announcement

Faeth Therapeutics (Faeth), a clinical-stage biotechnology company focused on metabolism, and The GOG Foundation, Inc. (GOG-F), a not-for-profit organization with the purpose of promoting excellence in the quality and integrity of clinical and translational scientific research in the field of gynecologic malignancies, today announced the first patient has been dosed in its Phase 2 combination trial of PIKTOR, which is FTH-001 (serabelisib) and FTH-003 (sapanisertib) with paclitaxel. The trial is the most advanced of its kind to investigate a novel approach of dual PI3Kɑ-mTORC1/2 inhibition targeting cancer metabolism in patients with endometrial cancer.

13-Mar-2025

Mayo Clinic researchers identify proteins linked to immunotherapy resistance in metastatic colorectal cancer

Mayo Clinic
Peer-Reviewed Publication

A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with metastatic colorectal cancer. In findings published in Clinical Cancer Research, the team identified specific proteins — fibronectin and smooth muscle actin — within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.

Journal: Clinical Cancer Research

13-Mar-2025

UTEP Researchers develop portable, blood-based device that detects colon cancer

University of Texas at El Paso
Peer-Reviewed Publication

Scientists at The University of Texas at El Paso are developing a less invasive portable device that would use blood samples to detect colorectal cancers. Their device is described in a new study published in the journal ACS Measurement Science Au.

Journal: ACS Measurement Science Au
Funder: U.S. National Science Foundation

13-Mar-2025

CityUHK researchers develop an innovative bio-detection platform for cancer early screening and disease monitoring

City University of Hong Kong
Grant and Award Announcement

Cancer continues to be a leading cause of mortality worldwide, highlighting the urgent need to develop more advanced, efficient, and early detection methods. Addressing this critical need, City University of Hong Kong (CityUHK) is leading a groundbreaking research project aimed at developing an innovative technology platform for early detection of cancer and personalised treatment. The project aims specifically to enhance the detection of circulating tumor cells (CTCs), paving the way for significant advancements in cancer diagnosis and care. This is one of the first batch of projects that has secured funding by the RAISe+ Scheme.

Funder: Research, Academic and Industry Sectors One-plus Scheme (RAISe+)

13-Mar-2025

High sugar-sweetened beverage intake and oral cavity cancer in smoking and nonsmoking women

JAMA Network
Peer-Reviewed Publication

High sugar-sweetened beverage intake was associated with a significantly increased risk of oral cavity cancer in women, regardless of smoking or drinking habits, yet with low baseline risk in this study. Additional studies are needed in larger cohorts, including males, to validate the impact of these findings.

Journal: JAMA Otolaryngology–Head & Neck Surgery

13-Mar-2025

Combination immunotherapy before surgery may increase survival in people with head and neck cancer

University of North Carolina Health Care
Peer-Reviewed Publication

Head and neck squamous cell carcinomas responded better to a combination of two immunotherapies than to one immunotherapy drug, according to a study in Cancer Cell. In addition, an analysis of the tumors after one month of immunotherapy identified which type of immune cells were activated to fight the cancer. These insights could help individualize treatment benefits.

Journal: Cancer Cell
Funder: NIH/National Institutes of Health, NIH/National Cancer Institute, Bristol-Myers Squibb

13-Mar-2025

Checking PSA levels too soon after prostate cancer surgery can lead to overtreatment

Mass General Brigham
Peer-Reviewed Publication

A cohort study of over 40,000 patients suggests that levels should be monitored for at least three months — longer than commonly practiced

Journal: JAMA Oncology

13-Mar-2025

Moffitt study finds new immunotherapy strategy for enhancing melanoma treatment

H. Lee Moffitt Cancer Center & Research Institute
Peer-Reviewed Publication

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO. Their study, published in the Journal for ImmunoTherapy of Cancer, shows that blocking MARCO in combination with a type of immunotherapy known as anti-CTLA4 therapy, significantly enhances tumor regression in melanoma, the deadliest form of skin cancer.

Journal: Journal for ImmunoTherapy of Cancer
Funder: NIH/National Cancer Institute

13-Mar-2025

Research team from Wesley Center for Immunotherapy at UH Seidman Cancer Center Awarded Top Scoring Abstract Award at the 2025 International Society for Cell and Gene Therapy Annual Meeting

University Hospitals Cleveland Medical Center
Grant and Award Announcement

Research team from Wesley Center for Immunotherapy at UH Seidman Cancer Center Awarded Top Scoring Abstract Award at the 2025 International Society for Cell and Gene Therapy Annual Meeting

David Wald, MD, PhD and colleagues abstract was selected based on their work to develop a less than one day CAR T-cell Therapy Manufacturing Process

13-Mar-2025

Researchers at Case Western Reserve University identify RNA molecule as possible driver of gastric cancer

Case Western Reserve University
Peer-Reviewed Publication

Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development of gastric cancer.

Journal: Gastro Hep Advances