EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 19-Sep-2025 13:11 ET (19-Sep-2025 17:11 GMT/UTC)

Study reveals targetable mechanism behind high-risk predisposition gene in pediatric medulloblastoma

St. Jude Children's Research Hospital
Peer-Reviewed Publication

Scientists at St. Jude Children’s Research Hospital showed how inheriting a deficient ELP1 gene increases the risk of SHH-driven pediatric medulloblastoma and further revealed that MDM2 inhibitors can help stop it.

Journal: Cancer Cell

How rearranged genes drive kidney cancer progression

Johns Hopkins Medicine
Peer-Reviewed Publication

In findings from a study led by investigators at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins Bloomberg School of Public Health, scientists report that they have learned how certain combinations of rearranged genes can promote the progression of a rare type of kidney cancer.

Journal: Cell Reports
Funder: Department of Defense Kidney Cancer Idea Development Award, National Institutes of Health National Institute of General Medical Sciences, National Cancer Institute, National Human Genome Research Institute, Jayne Koskinas Ted Giovanis, Johns Hopkins Provost Catalyst Award

Allen Institute launches CellScapes initiative to transform our understanding of how human cells build tissues and organs

Allen Institute
Business Announcement

The Allen Institute today announced the launch of CellScapes, a bold new research initiative aimed at revolutionizing how scientists understand and predict the behavior of human cells as they work together to build tissues and organs. The goal: to uncover the rules and principles of how cells cooperate to make decisions in the body and provide scientists with the tools to predict—and even design—how cells behave together in health and disease.

Shorter radiation therapy after prostate surgery safe, study finds

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

UCLA researchers found that stereotactic body radiotherapy (SBRT), a form of high-dose radiation delivered in just five sessions, is as safe as conventional treatment, with similar side effects and a similar impact on quality of life.

Journal: JAMA Oncology
Funder: NIH/National Institutes of Health, U.S. Department of Defense

Long-term survival in patients with low-risk cervical cancer after simple, modified, or radical hysterectomy

JAMA Network
Peer-Reviewed Publication

About The Study: In this cohort study, long-term survival was similar following simple hysterectomy vs modified radical hysterectomy or radical hysterectomy, supporting the use of simple hysterectomy in select patients with low-risk early-stage cervical carcinoma.

Journal: JAMA Network Open

South African study identifies two new breast cancer genes in black women

University of the Witwatersrand
Peer-Reviewed Publication

South African scientists have identified two new breast cancer genes—RAB27A and USP22—in Black women, marking the first GWAS of its kind on the continent. This breakthrough highlights the need for Africa-centred genomic research and tools to improve cancer risk prediction and treatment.

Journal: Nature Communications

Mass General Brigham study finds that patients with glioblastoma who received gabapentin lived longer

Mass General Brigham
Peer-Reviewed Publication

A new study by investigators from Mass General Brigham suggests that gabapentin, a relatively common anti-seizure/pain medication, is linked to improved survival in patients with glioblastoma (GBM) — the most common and deadly form of brain cancer in adults. The findings, published in Nature Communications, are based on a retrospective analysis and add new evidence to help patients with this devastating disease.

Journal: Nature Communications

Breakthrough in anal cancer treatment

University of Leeds
Reports and Proceedings

A kinder treatment for anal cancer involving a lower dose and shorter course of radiotherapy is more effective than traditional treatment, a clinical trial led by Leeds researchers has found.

Funder: Cancer Research UK, Stand Up To Cancer
Meeting: ESTRO 2025

Dual role of aurora kinase inhibition in liver cancer: Blocking proliferation and promoting differentiation

Science China Press
Peer-Reviewed Publication

A recent study demonstrates that Aurora kinase inhibitors can induce functional differentiation in liver cancer cells, offering a potential therapeutic strategy for liver cancer.

Journal: Science China Life Sciences

Enzyme identified as an important tumour inhibitor in T-cell lymphomas

Medical University of Vienna
Peer-Reviewed Publication

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of non-Hodgkin's lymphomas and is a rare but aggressive form of T-cell lymphoma that usually occurs in children and young adults. Research teams from the Medical University of Vienna at the Comprehensive Cancer Center of MedUni Vienna and University Hospital Vienna, in collaboration with the European Institute of Oncology (Turin, IT), Boston Children's Hospital and Harvard Medical School (US) and the University of Cambridge (UK), among others, have now been able to prove the function of epigenetic changes in the development of this cancer. The study has been published in the journal Leukemia.

Journal: Leukemia