EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 1-May-2025 03:08 ET (1-May-2025 07:08 GMT/UTC)

Allostatic load, educational attainment, and risk of cancer mortality among us men

JAMA Network
Peer-Reviewed Publication

About The Study: This study highlights the detrimental association of not attaining a high school degree, combined with high allostatic load as a marker of chronic stress, with cancer mortality. Efforts to promote educational attainment and address the underlying social determinants of health are imperative in reducing cancer disparities in this population.

Journal: JAMA Network Open

Geriatric surgery verification program can improve outcomes for older cancer patients in community hospitals

American College of Surgeons
Peer-Reviewed Publication

Implementing the American College of Surgeons (ACS) Geriatric Surgery Verification (GSV) program leads to better postoperative outcomes and preserves independence in older cancer patients undergoing major abdominal procedures, according to a new study published in the Journal of the American College of Surgeons (JACS).

Journal: Journal of the American College of Surgeons

Gene variant common in individuals of African ancestry may lead to reduced metabolism of the thiopurine class of drugs

Elsevier
Peer-Reviewed Publication

Mayo Clinic researchers found that a gene variant, the TPMT∗8 allele, is associated with reduced metabolism of the thiopurine class of drugs. TPMT∗8 is relatively common in individuals of African or African American descent. A novel study in The Journal of Molecular Diagnostics, published by Elsevier, details the researchers' goal to provide pharmacogenomic testing that can be used clinically to predict drug response that is beneficial to all patients, regardless of their ancestral background.

Journal: Journal of Molecular Diagnostics

Prostaglandin E2’s role in senescence and neoplastic escape in human keratinocytes

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY- December 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 16, Issue 21 on November 18, 2024, entitled, “Prostaglandin E2 regulates senescence and post-senescence neoplastic escape in primary human keratinocytes.”

Journal: Aging-US

St. Jude names Maria Megdal as executive vice president and chief administrative officer

St. Jude Children's Research Hospital
Business Announcement

Medgal will oversee departments vital to St. Jude operations. She previously led operations at major cancer centers in Boston and New York.

Autologous stem cell transplants do not improve survival for mantle cell lymphoma patients with undetectable MRD, clinical trial shows

ECOG-ACRIN Cancer Research Group
Reports and Proceedings

Late-breaking research reveals there is no benefit from high-dose chemotherapy followed by autologous stem cell transplant (ASCT) for patients with mantle cell lymphoma (MCL) in remission following their initial treatment. The finding is from the phase 3 study EA4151, by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN), presented December 10th at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego.

Funder: NIH/National Cancer Institute

Rice’s Veiseh elected to the National Academy of Inventors

Rice University
Grant and Award Announcement

Rice bioengineer Omid Veiseh has been elected as a National Academy of Inventors Fellow, the highest professional distinction awarded to inventors.

Ultra-processed foods may drive colorectal cancer risk, USF-TGH study finds

University of South Florida
Peer-Reviewed Publication

The study suggests that ultra-processed foods and inflammatory seed oils used in packaged food products may contribute to chronic inflammation, fueling colorectal cancer. Its findings pave the way for a new therapy -- resolution medicine -- which uses natural products in lieu of synthetic drugs to help reverse inflammation and potentially reverse colorectal cancer.

Journal: Gut

Using ‘biological age’ to predict early colorectal cancer risk

University of Miami Miller School of Medicine
Peer-Reviewed Publication

New research suggests that one’s biological age, which can be higher than his or her chronological age – a concept called accelerated aging – may predict who’s at risk for developing colon polyps, a known risk factor for colorectal cancer.

Journal: Cancer Prevention Research
Funder: ASCO Conquer Cancer Career Development Award, Sylvester Comprehensive Cancer Center, Woman’s Cancer Association of the University of Miami

Late-stage breast cancer diagnosis on the rise in US

Radiological Society of North America
Peer-Reviewed Publication

The number of women with late-stage, invasive breast cancer at the time of diagnosis increased significantly among U.S. women across all ages and ethnicities between 2004 and 2021.

Journal: Radiology