EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 6-Dec-2025 22:11 ET (7-Dec-2025 03:11 GMT/UTC)

3-Dec-2025

Breast density notification increases levels of confusion and anxiousness among women

University of Sydney
Peer-Reviewed Publication

New research by experts at the University of Sydney shows that breast density notification is leaving some women confused and anxious about their breast health. Breast density notification is being rolled out across Australia, but evidence suggests that women do not feel more informed by it. Between 25 and 40 percent of women have denser breast tissue which can make it harder for cancers to be detected through a mammogram.

Journal: BMJ
Funder: National Health and Medical Research Council

3-Dec-2025

Telling women as part of mammography screening that they have dense breasts may have unintended effects

BMJ Group
Peer-Reviewed Publication

Recommendations introduced in Australia and being considered in the UK to tell women if they have dense breasts as part of their screening results may have unintended effects and increase demand on health services, finds a clinical trial designed to assess the real-world impact of notification, published by The BMJ today.

Journal: The BMJ
Funder: National Health and Medical Research Council, National Breast Cancer Foundation, Cancer Screening Unit, Department of Health, Queensland Government

3-Dec-2025

Research reveals how disordered protein regions contribute to cancer-causing condensates

St. Jude Children's Research Hospital
Peer-Reviewed Publication

A machine learning-based resource developed at St. Jude Children’s Research Hospital predicts which intrinsically disordered regions can drive the formation of biomolecular condensates and links those proteins to RNA biology.

Journal: Science Advances

3-Dec-2025

Researchers identify target to overcome treatment resistance in preclinical models of KRAS-mutant cancers

University of Texas M. D. Anderson Cancer Center
Peer-Reviewed Publication

Researchers identified that RASH3D19 creates a positive feedback loop that drives hyperactivity of RAS signaling and leads to tumor growth and treatment resistance

Reducing RASH3D19 also reduced tumor growth and sensitized cancer cells to KRAS inhibitors

Combining RASH3D19 blockers with KRAS inhibitors improved outcomes in preclinical models

Journal: Nature Cell Biology

3-Dec-2025

Study shows common childhood virus can drive bladder cancer development

University of York
Peer-Reviewed Publication

A study published in Science Advances by Dr Simon Baker and colleagues at the University of York, suggests that a virus most people pick up in childhood can trigger the type of DNA damage that can lead to bladder cancer later in life.

Journal: Science Advances

3-Dec-2025

Identifying genes that keep cancer from spreading

University of Pennsylvania
Peer-Reviewed Publication

A collaborative study led by biomedical researchers Chris Lengner and M. Andrés Blanco at the School of Veterinary Medicine at the University of Pennsylvania has identified two genes that suppress colorectal cancer metastasis. “Metastasis is the almost universal killer in cancer,” Blanco says. “With a couple of exceptions, it’s what kills cancer patients.”

Journal: Proceedings of the National Academy of Sciences
Funder: NIH/National Institutes of Health, NIH/National Cancer Institute, Calico Life Sciences

3-Dec-2025

Women who receive mammograms also undergo lung scans if notified of eligibility

Vanderbilt University Medical Center
Peer-Reviewed Publication

While most women over age 50 schedule mammograms for breast cancer, only a minority who are also eligible for low-dose CT scans for lung cancer undergo those potentially lifesaving screenings. A new study shows that targeted outreach can close the gap.

Journal: Journal of the American College of Radiology

3-Dec-2025

Mental health conditions may heighten liver cancer risk in veterans due to increased hepatitis C, UCLA study finds

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

A new study led by UCLA Health Jonsson Comprehensive Cancer investigators found that mental health conditions, especially alcohol use disorder and post-traumatic stress disorder (PTSD), significantly increase the likelihood of developing liver cancer among U.S. veterans living with cirrhosis of any cause.

Journal: Clinical Gastroenterology and Hepatology

3-Dec-2025

New model demonstrates how a dynamic mechanism regulates traffic through the nuclear pore complex

Rockefeller University
Peer-Reviewed Publication

The nuclear pore complex (NPC) controls what moves in and out of the cell nucleus. Scientists have long debated how its flexible components team up with transport factors to create a barrier that is both fast and highly selective. Using high-speed atomic force microscopy and synthetic nanopores, the researchers showed that transport factors continuously reorganize the NPCs central transporter to enhance its selectivity and speed. The findings overturn previous rigid or gel-like models of the nuclear pore complex, offering new insight into diseases—such as cancer and neurodegeneration—that are linked to NPC breakdown. They also provide a blueprint for designing smart, nanopore-based technologies for drug delivery and filtration.

Journal: Nature Cell Biology

3-Dec-2025

How two Russian scientists changed the way we understand aging and cancer

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY — December 3, 2025 — A new essay was published in Volume 17, Issue 11 of Aging-US on November 19, 2025, titled “On the intergenerational transfer of ideas in aging and cancer research: from the hypothalamus according to V.M. Dilman to the mTOR protein complex according to M.V. Blagosklonny.”

Journal: Aging-US