The Chinese Medical Association has released new guidelines for diagnosing and treating Mycoplasma pneumoniae in children. Addressing challenges like variable symptoms and rising antibiotic resistance (81% for macrolides in China), experts recommend PCR testing for accurate diagnosis, macrolides for mild cases, and tetracyclines for severe infections in older children. Corticosteroids are also advised for severe cases, and judicious antibiotic use is stressed to combat resistance and improve treatment outcomes.

It’s time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March 18^th in the open-access journal PLOS Biology.

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and their association with certain diseases, such as inflammatory bowel disease (IBD) or colorectal cancer, has only recently become known. The Fish Genetics Research Group of the Department of Genetics at ELTE has investigated in detail the temporal expression of snoRNAs in the genome of zebrafish, an important genetic model organism, and has also created an online database (snoDanio) for their interactive visualization.