How fixed structural wiring supports a flexible brain?
Peer-Reviewed Publication
Updates every hour. Last Updated: 27-Oct-2026 04:16 ET (27-Oct-2026 08:16 GMT/UTC)
A study published online in Science Bulletin introduces structural connectome embeddedness, a state-level dimension describing how deeply each momentary whole-brain activity pattern is embedded in the topology of anatomical connections. Evidence from whole-brain biophysical modeling, macroscale functional organization patterns, and multimodal imaging in 713 Human Connectome Project participants supports the concept's biophysical grounding and prevalence. High-CoDE moments help anchor stable functional connectivity, individual variability relates to a behavioral dimension associated with mental health and clinical vulnerability, and task-evoked embeddedness increases with cognitive demand. The framework helps explain how a stable connectome organizes flexible brain activity.
Researchers recovered five multidrug-resistant Stutzerimonas nitrititolerans isolates from 60 geese fecal samples collected at a farm in Yangzhou, China. Genome sequencing showed that all five carried chromosomal tmexC2D2-toprJ2 and blaPST-2 resistance-associated determinants. Across 104 available genomes, complete tmexCD-toprJ clusters were uncommon, and only nine genomes carried both a complete tmexCD-toprJ cluster and blaPST, five of which were the geese isolates.
Researchers used combinatorial solid-phase peptide synthesis and infrared thermography to screen 300 tripeptide sequences for interactions with CO2. Two tripeptides, His(Boc)-Phe-Asn and Phe-Ala-Glu(OtBu), showed reproducible thermal responses after CO2 exposure. The signals were reproduced on glass, functionalised cellulose, and Rink-amide resin, indicating that thermographic screening can help identify peptide candidates for further development as bioinspired CO2-binding materials.
Researchers fabricated ultralight anisotropic SiC aerogel using corn‑stalk biomass as raw material. The study, published in Defence Technology, reveals that the material exhibits orientation‑dependent electromagnetic‑wave absorption and outstanding high-temperature insulation performance, clarifying structure‑function coupling effects of biomass‑derived anisotropic ceramic aerogels and offering a green fabrication route for adaptive multifunctional protective materials.