A review published in UroPrecision synthesizes clinical evidence on high-intensity focused ultrasound for localized prostate cancer and highlights that intraoperative prostate compression is a promising technical refinement that enhances treatment precision and outcomes.

A review published in UroPrecision synthesizes current knowledge on prostatic stromal tumor of uncertain malignant potential (STUMP), a rare prostatic neoplasm with unpredictable clinical behavior. The review, based on 84 patients from 14 studies, highlights the demographic, clinical, and pathological characteristics, diagnostic approaches, and treatment modalities for STUMP.

High glucose uptake by cancer cells is one of the most widely recognized features of tumor metabolism and provides an important biological basis for positron emission tomography/computed tomography (PET/CT) imaging. Although this phenotype is commonly attributed to the energetic and biosynthetic demands of rapid proliferation, glucose-derived carbon is also distributed among multiple downstream pathways.

A research team has uncovered a multilayered regulatory network that controls pear seed germination by integrating metabolomic, transcriptomic, and microRNA analyses. 

Myopia has become a major global public health concern. It is not simply a matter of blurred distance vision: as the eye continues to elongate, high myopia can increase the risk of macular lesions, choroidal neovascularization, retinal degeneration, and retinal detachment. With myopia rising among children and adolescents, current management increasingly combines behavioral measures, optical interventions, and pharmacological treatment. While atropine has long been the best-known option, uncovering how these medications work to slow myopia progression is far more complex than expected.

A review titled Pharmacological Management of Myopia: Emerging Agents and Novel Molecular Targets published in Eye Discovery brings together current and emerging pharmacological approaches for myopia control. Written by Tong Zhao of Nanjing Medical University and Meiyan Li of the Eye & ENT Hospital of Fudan University, the article reviews established and investigational agents, including atropine, pirenzepine, 7-methylxanthine (7-MX), and intraocular pressure-lowering drugs. It also discusses emerging molecular targets linked to endoplasmic reticulum stress, ferroptosis, signaling pathway modulation, and epidermal growth factor receptor (EGFR) blockade.

A research team has identified an optimal lipid range for granulated microdiets in largemouth bass larvae, showing that dietary fat can strongly shape growth, feed efficiency, nutrient retention, liver condition, and intestinal development.

Researchers report a programmable mid-infrared photothermoelectric detector based on a suspended nanometer-thick SrTiO₃ membrane. It responds in about 10 microseconds, reaches about 50 volts per watt through dual-gate control, and supports 40 measured response states. A 3-by-3 array further demonstrates programmable infrared image preprocessing and attention-guided thermal target enhancement.

Many vitreoretinal disorders, including retinal detachment (rhegmatogenous, exudative, or tractional), macular holes, proliferative vitreoretinopathy, diabetic retinopathy, and vitreous hemorrhage, often require vitrectomy with retinal repair, followed by intraocular tamponade to stabilize the retina and preserve ocular integrity. The tamponade agents most used in clinical practice are expansile gases and silicone oil. Although these materials can effectively support postoperative retinal reattachment, they remain limited in terms of long-term stability and biosafety. Complications such as cataract formation, elevated intraocular pressure, intraocular inflammation, and retinal injury associated with silicone oil emulsification may still occur. To address this challenge, Prof. Jianhai Yang and Prof. Wenguang Liu (Tianjin University), together with Prof. Xiaorong Li and Prof. Xiaoli Xing (Tianjin Medical University Eye Hospital) developed an injectable zwitterionic polymer hydrogel based on poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC).

A recent study published in National Science Review, based on Chang'e-6 (CE6) farside samples, has shown that the lunar mantle lacks a clear compositional dichotomy. The farside anorthositic crust is more magnesian, whereas late-stage products of the lunar magma ocean appear thinner on the farside. To reconcile these hemispheric variations spanning from the mantle to the crust, a coherent model of lateral thermal convection within the magma ocean of the tidally-locked Moon has been proposed.