Apricot breeding has long depended on a narrow genomic view, leaving much of the variation preserved in wild relatives outside the frame.

A research team has found that dyadic coping—the way couples jointly manage stress—partly explains the association between fear of cancer recurrence and depression among middle-aged and older survivors of gastrointestinal cancer. 

Duraplasty is a surgical procedure that is used to repair or reconstruct the dura mater using a patch graft. Several graft materials are used for the surgery, but their comparative safety remains uncertain. Now, researchers conducted a prospective randomized study in Central India to compare the outcomes of autologous pericranium (natural graft) with those of synthetic high-density polypropylene (G-Patch) in patients undergoing cranial duraplasty. Findings confirmed that both materials demonstrated acceptable short-term safety profiles.

A new study by Peking University shows that pressure measurements collected by smartphones can improve forecasts of a severe hailstorm over Beijing, suggesting that millions of smartphones could someday support a dense, low-cost observing network for faster and more accurate severe-weather warnings.

This research explores a new wireless implantable device designed to improve photodynamic therapy (PDT) for cancer treatment, particularly bladder cancer. By delivering light directly inside the body without wires, the system helps overcome the challenge of limited light penetration in traditional PDT. The study shows that the device can successfully generate the key molecules needed to destroy cancer cells, offering a promising step toward more precise, less invasive treatments in the future. 

A study in Chinese Medical Journal reports that SLC38A7, a lysosomal glutamine transporter, is overexpressed in gastric cancer and associated with poor prognosis. Using patient tissues, cell models, mutational analyses, and mouse xenografts, the researchers show that SLC38A7 binds MYH9, promotes GSK-3β ubiquitination and degradation, and activates Wnt/β-catenin signaling. The findings identify a metabolically linked oncogenic pathway, clarify a previously unrecognized disease mechanism, and suggest a potential therapeutic target for gastric cancer.

Steroid-induced osteonecrosis of the femoral head (SONFH) can prevent damaged bone from healing, often leading to joint collapse and disability. Researchers have now developed a coral-inspired, 3D-printed scaffold that reprograms immune cells to create a healing environment for bone repair. In vitro and in vivo studies showed that the scaffold promoted angiogenesis and bone regeneration, offering a promising strategy for overcoming the disease's underlying immune dysfunction and improving bone repair.

A study of non-functional pancreatic neuroendocrine tumors (NF-PanNETs) identified an AGR2^high endocrine subcluster enriched in high-grade tumors and showed that simple AGR2 immunohistochemistry serves as a clinically informative prognostic marker. Mechanistically, the transcription factor FOXM1 directly drives the proliferative transcriptional program of AGR2^high cells, while chemical inhibition of FOXM1 showed therapeutic benefit in tumor cells, patient-derived organoids, and xenograft models. Together, the findings provide a new approach for prognostic stratification and identify FOXM1 as a potential therapeutic vulnerability in NF-PanNETs.

Researchers led by Prof. WANG Qihui and Prof. George F. Gao from the Institute of Microbiology of the Chinese Academy of Sciences have mapped how antibodies target a key region of the virus's spike protein, how they neutralize the virus, and how emerging variants escape them.

Eco-nanozymology, as an emerging interdisciplinary field, integrates nanotechnology with principles of enzymology to offer innovative strategies for energy conversion and environmental remediation. In contrast with conventional enzymology, eco-nanozymology enhances catalytic efficiency through the precise regulation of interfacial microstructures, electronic distributions, active site configurations, multienzyme cascade catalysis, and functionalized carrier engineering. By harnessing and amplifying natural ecological processes, eco-nanozymology enables effective modulation of energy flow and material cycling within ecosystems. This review focuses on recent advances in the application of eco-nanozymology across energy-related domains, including nitrogen fixation, carbon fixation, methane oxidation, hydrogen production, and energy conversion devices. It further provides an in-depth analysis of the recent progress in the efficient degradation of environmental pollutants and resource-oriented valorization of low-value biomass, such as lignin, agricultural residues, livestock manure, and microplastics. These studies highlight the pivotal role of eco-nanozymology in enhancing the efficiency of environmental management, accelerating the development of green energy technologies, and advancing carbon neutrality goals. The continued development of eco-nanozymology is expected to open new horizons for the deepening and expansion of nanozyme applications, offering green, environmentally friendly, and sustainable technological pathways to address global energy and environmental challenges.