Biomarkers for predicting suicide risk in hospitalised patients with mental disorders have been understudied. Currently, suicide risk assessment tools based on objective indicators are limited in China. To examine the value of various biomarkers in suicide risk prediction and develop a risk assessment model with clinical utility using machine learning.

A recent review article published in Molecular Biomedicine highlights that a comprehensive understanding of reactive oxygen species (ROS) homeostasis is opening new avenues for therapeutic innovation. The review begins with the core principles and molecular mechanisms that govern ROS generation, scavenging, and organelle crosstalk, and then systematically elaborates how ROS dynamics influence cellular metabolism, growth, differentiation, and programmed cell death. It critically assesses how disruption of ROS homeostasis contributes to the pathogenesis of diverse diseases across the lifespan and synthesizes current and emerging strategies for modulating ROS levels. Emphasizing the need to resolve challenges of specificity and context-dependence, the authors call for the development of precise biomarkers and the exploration of combination approaches—such as pairing ROS modulators with immunotherapy or metabolic agents—to enhance efficacy. By framing ROS as both indispensable signaling mediators and potential toxins, the review argues that targeted modulation of ROS homeostasis could reshape future precision medicine, while urging more translational studies to validate and optimize these strategies for clinical use.

Australia produces over 31 million tonnes of food waste each year, creating serious challenges for both the environment and the economy. Researchers at the University of New South Wales and their international partners have reviewed how converting food waste into biochar, a carbon-rich material produced by heating organic matter without oxygen—could help tackle the country’s waste crisis while improving soil fertility and fighting climate change.

How does 3D printing precisely control battery stress?

In International Journal of Extreme Manufacturing, Wei Yuan and coworkers from South China University of Technology introduce a new manufacturing method for gel polymer electrolytes (GPEs) using digital light processing (DLP) 3D printing. This technique allows precise control over the structure of GPEs through layer-by-layer curing. It improves the uniformity of microscopic pores and macroscopic dimensions, which helps regulate interfacial stress effectively. This study offers a practical strategy to enhance the stability of the anode-electrolyte interface (AEI), contributing to zinc batteries with longer cycle lives.

A new study has revealed that sunlight can transform common synthetic fabrics into tiny plastic fibers that pollute coastal oceans. The findings shed light on how clothing and household textiles contribute to the growing problem of microplastic pollution in marine environments.

A new study reveals that a small but powerful component of biochar, known as dissolved organic matter, plays a surprisingly large role in capturing toxic lead from contaminated water. The research, published in Biochar, uncovers how this dissolved material enhances the metal-binding power of biochar and offers molecular-level insights that could guide safer and more effective cleanup strategies.

A research team from the Nanjing Institute of Geology and Palaeontology of the Chinese Academy of Sciences has made progress in studying the Shibantan Biota in Yichang, Hubei Province, uncovering the oldest known complex three-dimensional burrow systems to date. Preserved in approximately 550-million-year-old strata, these trace fossils show that complex animal behaviors were modifying the seafloor environment nearly 10 million years earlier than previously thought.

A new study has uncovered alarming evidence that bisphenols (BPs) —plastic-related chemicals known to disrupt hormones—are accumulating and magnifying through Arctic food webs. 

Power systems are among the most complex man-made systems. However, complexity is not inherently an advantage. In fact, complex dynamics are often the underlying cause of complicated stability issues. In the future 100% renewable power system, converter-interfaced generation (CIG) becomes the main form of power generation, the dynamic of which are dominated by control processes and can be reduced with proper control strategies. Following this idea, researchers at Tsinghua University propose a frequency-fixed grid-forming control (FF-GFM) that controls CIGs as constant voltage sources within their capability limitations. FF-GFM can reduce frequency dynamics and synchronization dynamics, greatly enhancing the stability and safety of the system.

Titled “A comparison of integration methods for single‐cell RNA sequencing data and ATAC sequencing data”, this paper provides a timely and in-depth analysis of the rapidly evolving field of single-cell multi-omics integration (Figure 1). As technologies advance to profile multiple molecular layers—such as gene expression and chromatin accessibility—researchers face increasing challenges in harmonizing and interpreting complex datasets.