Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent research by Chinese scientists has revealed novel molecular mechanisms by which HIRA acts in concert with dPCIF1 to establish a totipotent chromatin and facilitate orderly zygotic genome activation in the early embryos of Drosophila.

This study suggests that GERD may elevate cardiovascular risks, including increased blood pressure, unhealthy lipid levels, and a higher likelihood of heart disease. Through advanced genetic analysis, researchers linked GERD to elevated systolic and diastolic blood pressure, higher LDL cholesterol, and an increased risk of heart attack, highlighting GERD’s broader health implications.

Machine learning's predictive power is underutilized in vehicle-pedestrian risk identification, impeding proactive safety. A new model is needed to estimate crash severity, not just frequency. Researchers propose a novel framework combining machine learning and extreme value theory to estimate pedestrian crash frequencies by injury severity levels.

Researchers at the University of Natural Resources and Life Sciences, Vienna, and Institut Teknologi Sumatera, Indonesia, set out to explore the dynamics behind shared micromobility fleet development. By utilizing a system dynamics modeling approach, they examined how fleet size, user demand, regulatory policies, and economic factors interact to shape the success of these systems.

Researchers at the University of Natural Resources and Life Sciences, Vienna, and Institut Teknologi Sumatera, Indonesia, set out to explore the dynamics behind shared micromobility fleet development. By utilizing a system dynamics modeling approach, they examined how fleet size, user demand, regulatory policies, and economic factors interact to shape the success of these systems.

Researchers delved deep into the regulation of cobalt active sites to enhance the selectivity of propylene to improve scalability and affordability of the production of this important chemical.

A recent study unveils an innovative composite phase change material (CPCM) tailored for lithium-ion battery (LIB) thermal management. Using hydrated salts, this material is engineered to regulate battery temperatures and mitigate thermal runaway (TR) risks, paving the way for safer and more efficient battery applications. The research emphasizes the dual benefits of improved energy densities and longevity while addressing pressing safety concerns associated with high-rate charging and discharging.

In a study published in Science China Earth Sciences, research teams from China collaboratively reconstructed the tectonic evolution and sedimentary filling processes of the North Sea Basin through the lens of multi-spheric interactions. Their analysis reveals how deep dynamic processes, climate, and transgression evolution jointly controlled the formation and development of distinct gas-rich and oil-rich zones in the basin, while also discusses hydrocarbon exploration prospects in mid- to high-latitude regions.

Researchers from Qingdao University and the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences have developed a novel method for rapidly and accurately assessing the metastatic potential of cancer cells. The new tool— combining Raman spectroscopy and machine learning—introduces the Ramanome-based Metastasis Index (RMI), offering an innovative means of diagnosing and managing cancer.

In a review published in SCIENCE CHINA Chemistry, the phase and phase transition regulation of bismuth-based semiconductors (BBSs) were systematically presented based on the classification of BBSs. Notably, the critical factors for phase transition of BBSs, and intrinsic driving forces endowed by phases of BBSs for enhanced photocatalytic performances of organic contaminants removal were also elucidated.