In a recent breakthrough published in Optics & Laser Technology and Infrared Physics & Technology, a research team led by Prof. CHENG Tingqing at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences have introduced a novel low-thermal-effect gradient-doped crystal to tame thermal effects and improve brightness of high-power end-pumped Nd:YAG lasers.

Recently, the research team led by Professor HUANG Qing from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences successfully developed a series of CoNi- metal-organic framework (MOF) nanozymes with laccase-like activity using a gas-liquid interface dielectric barrier discharge (DBD) low-temperature plasma (LTP) technique. 

A research team at the Institute of Solid State Physics, the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has recently developed advanced aerogel composites that combine high-temperature insulation with mechanical load-bearing capabilities, while also achieving controllable fabrication of large-size samples.

In the production of dimethyl carbonate (DMC), a versatile chemical critical for manufacturing lithium-ion battery electrolytes, pharmaceuticals and high-performance polymers, an ultra-high purity (≥99.95%) is needed to meet stringent industrial standards. Melt crystallization, as a green manufacturing method is highly important for this purpose; however, the widespread adoption of this technology has been hindered by complex heat and mass transfer phenomena, which can lead to uneven crystal growth and suboptimal yields.

This study demonstrates that Setd2 overexpression rescues bivalent gene expression during zygotic genome activation (ZGA) in somatic cell nuclear transfer (SCNT) embryos, significantly improving cloning efficiency. By mapping H3K4me3 and H3K27me3 dynamics in mouse SCNT embryos, researchers identified aberrant hyperaccumulation of these histone marks at promoter regions during ZGA, leading to dysregulated bivalent gene expression. Overexpression of Setd2, the H3K36me3 methyltransferase, restored chromatin balance by antagonizing H3K27me3 deposition and enhancing transcriptional activation of ZGA-critical genes, thereby increasing blastocyst formation rates.

Patients with glioblastoma (GBM)—a type of brain cancer—have a poor prognosis owing to the aggressive nature of GBM disease and limited GBM treatment options. A new study by researchers from Croatia provides critical insights into the transformative role of artificial intelligence (AI) in advancing the diagnosis and treatment of GBM. From accurately distinguishing tumor tissue in GBM to enabling personalized treatment, AI-based tools and models can revolutionize GBM treatment and care.

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in shaping immune responses within breast cancer microenvironment.

Cancer's ability to evade immune destruction often hinges on a stealthy process—CD8⁺ T cell exhaustion.

In a paper published in MedComm, embryologists and physicians in the field of reproductive medicine present evidence that DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and embryo development defects. It provided a theoretical basis and application values for clinical counseling, genetic diagnosis, and treatment strategies in infertile patients.

Forest fires cause irreversible ecological and economic losses worldwide, often exacerbated by delayed or inefficient rescue efforts. A new study presents a groundbreaking data-driven framework to revolutionize aviation emergency networks. By integrating fire probability predictions with multi-objective optimization, the research enables faster, cost-effective rescue planning tailored to real-world fire risks. Tested in China’s Hainan Province, the model reduces response times while balancing ecological and operational costs—offering a scalable solution for global forest protection.