Understanding jaw growth: Key gene axis controls postnatal condyle development
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Jan-2026 06:11 ET (20-Jan-2026 11:11 GMT/UTC)
A study published in the International Journal of Oral Science reveals that the PLAGL1-IGF2 axis plays a vital role in postnatal jaw development. Using a mouse model, researchers showed that PLAGL1 regulates osteoblast differentiation in cranial neural crest cell-derived condyles. Deficiency in PLAGL1 disrupts bone formation, but treatment with IGF2 can rescue this effect. These findings provide new insights into craniofacial development and potential therapeutic targets for mandibular disorders.
A research team has successfully engineered yeast cell factories to selectively secrete and produce vitamin A (retinoids), achieving record yields of retinol, retinal, and retinoic acid.
Programmed cell death (PCD) plays a central role in the development of multiple systemic diseases. In a recent review, researchers from China examined how Z-DNA binding protein 1 (ZBP1) regulates PCD and influences disease progression. They summarized the molecular mechanisms controlling ZBP1-mediated cell death, discussed interacting molecules and signaling pathways, and highlighted the potential of targeting ZBP1 as a therapeutic strategy for treating related pathological conditions.
Researchers discovered a previously unknown solar radio pattern — periodic beaded stripes — using the Chashan Broadband Solar Radio Spectrometer during a 2024 flare. These narrow, drifting radio bands, dotted with rhythmic “beads”, reveal rapid plasma processes in the Sun’s corona. The team attributes their formation to the double plasma resonance effect, modulated by magnetohydrodynamic waves. Observations suggest a weak magnetic field (~1 G) above the flaring loops in an active solar region.
Stainless steels are basic corrosion-resistant materials, but they still suffer from environmental erosions by ubiquitous chemical reactions, resulting in typical corrosion rates at dozens of mm∙yr-1. Here a strong-field laser passivation strategy is proposed, with which up to 100,000-fold reduction in the corrosion rates of AISI 304 is achieved respectively in saline, acidic, and alkaline solutions. The generality is exemplified by exhibiting the similar anticorrosion enhancements for AISI 316, 420, 201, 430 and 2205 steels.
This protocol provides a detailed guide for single-molecule tracking (sptPALM) in living microbial cells, specifically focusing on E. coli and Saccharomyces cerevisiae. It outlines the steps for sample preparation, data acquisition, and data processing, enabling researchers to visualize and quantify the dynamics of individual molecules within living cells.
A research team from Wuhan University has developed an innovative machine learning framework that accelerates the discovery of materials with tailored thermal properties. By combining interpretable deep learning with multiscale computational techniques, the team achieved highly accurate predictions of lattice thermal conductivity (LTC) while also shedding light on the underlying physical mechanisms. Their approach maintains the predictive power of traditional "black-box" models but adds the physical interpretability. As result, several high-performance materials for thermal management were identified. This advancement not only speeds up the development of efficient thermoelectric devices and thermal control systems but also provides deeper insights into the fundamental process of heat transfer at the atomic scale.
Recently, a review study led by Professor Xuejun Liu from the College of Resources and Environmental Sciences at China Agricultural University and Tianxiang Hao et al. systematically analyzed the current status of China’s farmland carbon budget, providing a scientific solution to this dilemma. The related paper has been published in Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2025602).
Recently, Guoqin Huang from Jiangxi Agricultural University and Kai Huang from Guangxi Hydraulic Research Institute systematically reviewed the multiple benefits of sugarcane intercropping in optimizing soil fertility. Their findings offer new insights for ecological restoration of dry sloping farmland in southern China. The related paper has been published in Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2025612).