Scientists have created a groundbreaking, fully implantable neurostimulator made entirely of soft hydrogel to treat inflammatory bowel disease (IBD). Unlike traditional rigid and wired implants, this wireless device gently wraps around the splenic nerve. It receives power through the skin to deliver electrical pulses that calm gut inflammation by rebalancing the immune system. In animal studies, the device significantly alleviated colitis symptoms without causing scar tissue formation, paving the way for a new class of soft, bioelectronic therapies for chronic diseases.

Scientists have developed a novel Cr-based single-atom catalyst that enables highly efficient hydrogen peroxide (H₂O₂) production in acidic environments through an electrochemical process. This breakthrough, guided by molecular dynamics simulations, reveals a self-adjusting mechanism with the catalyst actively restructuring during the reaction, achieving exceptional selectivity that rivals or even surpasses that of conventional Co-based catalysts.

Scientists in China have engineered topology-driven energy transfer networks in lanthanide-doped upconversion nanoparticles to dramatically reduce the laser power needed for stimulated emission depletion (STED) microscopy. By spatially separating sensitizers and emitters in core–shell nanoparticles, they enhanced energy migration, boosted emission, and improved optical switching efficiency. Their design achieves STED microscopy imaging with significantly lower excitation and depletion intensities, paving the way for low-power, photostable super-resolution imaging in life sciences and nanophotonics.

In 20th-century biochemistry history of China, Szu-Chih Liu (刘思职, 1904—1983)(Fig. 1) acted as a central bridge in both academic genealogy and knowledge indigenization. Liu inherited the methodology and value established by Chinese earliest generation of biochemistry trailblazers, notably Hsien Wu, while fostered generations of biomedical students.

Recently, a research team led by Academician Lijun Wang at CIOMP under UCAS has systematically reviewed the latest advancements in transfer printing (TP) technology. The team detailed its practical applications in integrating III-V semiconductor devices into photonic integrated circuits (PIC), demonstrating its significant potential for developing high-performance, high-reliability PICs. Their work provides crucial theoretical guidance for improving transfer yield and precision, while also offering forward-looking insights into current technical challenges and future development directions for this technology.

An innovative CRISPR-Cpf1-endo-recombinase CauR co-edited platform was developed and successfully applied to the glutamate-producing strain Corynebacterium glutamicum S9114 for high-efficiency production of N-acetylglucosamine (GlcNAc).

A study on the engineering of thermostable endo-polygalacturonase has opened up a new and efficient way for the production of functional oligosaccharides.

A recent study comprehensively evaluated the secondary metabolite diversity and in vitro antidiabetic activity of Sanghuangporus quercicola under various culture conditions, highlighting the medicinal fungus’s immense potential for developing new antidiabetic drugs and functional foods.