Neoadjuvant therapies, or treatments given before surgery, are changing how doctors treat locally advanced colon cancer. In a recent review, researchers from the United States examined how pre-surgical chemotherapy and immunotherapy can shrink tumors, reduce recurrence, and improve surgical outcomes. They discussed clinical trials like FOxTROT and NICHE and highlighted the importance of using mismatch repair (MMR) status to guide treatment decisions and improve patient outcomes through personalized care strategies.

A research team has studied the development of the Shanghai Typhoon Model from a traditional physics-based regional model toward a data-driven, machine-learning typhoon forecasting system. They summarize the model’s performance in Typhoon Danas in 2025, noting that a hybrid Shanghai Typhoon Model provides a significant advancement in forecast accuracy. Their paper outlines a roadmap for evolving the physically driven Shanghai Typhoon Model into a purely data-driven, regional machine-learning weather-prediction model designed for typhoon prediction.

Researchers led by Prof. George F. Gao from the Institute of Microbiology of the Chinese Academy of Sciences (CAS) have identified the key mechanism by which F. nucleatum binds to the human cell receptors CEACAM1 and CEACAM5, which are frequently overexpressed on many types of cancer cells.

Researchers present a data‑driven media monitoring system that turns newspaper content into early‑warning risk signals for anti‑money laundering (AML) supervision. Using entity- and theme-based keywords scored with BM25 and aggregated into weekly indicators, the system flags periods requiring analyst attention. Event analysis of eight ICIJ offshore leaks (2013–2021) shows timely detection for Belgian banks; robustness checks assess machine translation and a prompt‑based alternative.

Current clinical protocols predominantly utilize mononuclear gadolinium(III) complexes as contrast agents. Recently, coordination clusters composed of multi-nuclear paramagnetic metal ions have demonstrated promisingly higher relaxation rates as MRI contrast agents and adaptable stability in various solutions, offering promising medical application prospects. This review mainly highlights such advancements, focusing on the influence of ligand selection and structural design on the relaxation rates of metal clusters as MRI contrast agents.

A comprehensive study of 238 high-oil peanut varieties in China reveals key insights into their agronomic traits, disease resistance, and genetic diversity. While these varieties show promising oil content (up to 61%), they face challenges such as a trade-off between oil and protein content and limited high-level disease resistance. The findings provide a foundation for future breeding strategies to enhance yield, quality, and resilience.

The AP2/ERF transcription factor SHAT2 positively regulates seed shattering and quality. SHAT2 mutation affects the expression of seed-shattering and quality-related genes. SHAT2 regulates the expression of seed development-related genes through interaction with the GCC-box.

Two-photon upconversion is an emerging technique to probe excitonic dark states. Towards high-efficiency upconversion, scientists in China employed a doubly resonant plasmonic nanocavity, achieving 2440-fold enhancement of two-photon luminescence due to improved light collection, magnified excitation rate and increased quantum efficiency. To clarify the physical mechanism, single-resonance-enhanced second-harmonic generation and photoluminescence alongside thermally tuned dual-resonance upconversion are investigated. These results establish a foundation for developing high-performance nonlinear photonic devices and probing fine excitonic states.