Many women experience cognitive fog or memory impairment during pregnancy or while taking oral contraceptives. A new study published in Science Bulletin reveals that sustained high levels of estrogen disturb a specific neural circuit connecting the lateral hypothalamus to the hippocampus, leading to temporary memory loss. This discovery provides a long-sought biological explanation for "mom brain" and reconciles decades of conflicting data on estrogen's effects on memory

Large-aperture optical mirrors are critical to astronomical observation, and their fabrication requires full-chain technologies spanning blank preparation, deterministic polishing, cross-scale metrology, and acceptance testing. A review highlights a closed-loop manufacturing-testing paradigm for continuous surface-error correction, while identifying sub-nanometer full-frequency precision control, intelligent adaptive integration, and in-orbit manufacturing as key directions for future ultra-large-aperture mirrors.

Micro-QLEDs are emerging as a promising AR technology due to their high brightness and high-resolution capability. Scientists in China developed a two-inch wafer-scale fabrication process for Micro-QLEDs which provides a simple and low-cost route to accelerate the industrial application of Micro-QLED display.

A phase 3 randomized controlled trial involving 614 patients with acute ischemic stroke who did not receive reperfusion therapy found that oral edaravone (TTYP01) initiated within 24 hours of symptom onset and continued for 28 days significantly improved functional outcomes. At 90 days, 65.4% of patients in the treatment group achieved excellent functional recovery (mRS 0–1) compared with 47.1% in the placebo group (OR 2.12, 95% CI 1.53–2.94, P <0.001). No significant differences in safety events were observed between the two groups.

Endometriosis (EM) and uterine leiomyoma (UL) are common gynecological disorders with substantial clinical overlap; however, their shared epidemiological and genetic underpinnings remain poorly understood. This study investigated comorbidity between EM and UL using epidemiological, genetic, and molecular analyses.

To assess the global, regional, and national burden and trends of endometriosis-related infertility in women of reproductive age. Data were extracted from the Global Burden of Disease Study 2021. We analyzed the number of cases, all-age and age-standardized prevalence rates, and relative changes globally, regionally, and nationally, stratified by age and sociodemographic index (SDI) quintiles. An age-period-cohort model was used to estimate net drifts, local drifts, and period/cohort-specific relative risks from 1990 to 2021.

In the International Journal of Extreme Manufacturing, researchers have developed a technique that uses electric fields to anchor and stretch liquid metal, allowing it to freeze in mid-air to form unsupported 3D circuits.

This review highlights microneedle-based cosmetic delivery as a minimally invasive strategy for overcoming the skin barrier and improving intradermal delivery of active ingredients. It summarizes advances in solid, coated, dissolving, hollow, and hydrogel-forming microneedles, together with their materials, fabrication methods, and delivery mechanisms. Key cosmetic applications include anti-aging, skin rejuvenation, pigmentation control, acne management, hydration, barrier repair, and hair-growth treatments. The review also discusses safety, regulation, consumer acceptance, commercialization, and emerging innovations such as smart, stimuli-responsive, personalized, wearable, and IoT-integrated microneedle systems, emphasizing their potential to transform conventional topical skincare into precise, controlled, next-generation dermal delivery platforms for aesthetic dermatology.

Reliable battery operation in sub-zero environments is critical for polar exploration, military missions, and space applications. However, conventional lithium-ion batteries (LIBs) face inherent limitations at low temperatures by intrinsic hurdle of poor ionic mobility in liquid electrolytes. All-solid-state batteries (ASSBs), which replace liquid electrolytes with non-flammable and non-freezing solid electrolytes, are considered promising alternatives because these solid electrolytes provide high ionic conductivity at low temperatures, superior temperature stability, and exceptional safety. ASSBs still face practical limitations at extremely low temperatures due to degradation caused by interfacial side reactions and mechanical instabilities that increase resistance and polarization. Addressing these challenges is critical to realize the advantages of ASSBs and enable their practical deployment in low-temperature applications. This review provides an overview of historical developments, critical challenges, and recent progress in advancing the low-temperature performance of ASSBs. The key components of ASSBs, including solid electrolytes, cathodes, and anodes, are systematically investigated to develop strategies for improving ASSBs at low temperatures. By highlighting future perspectives, we emphasize both the potential and necessity of ASSBs to overcome the intrinsic limitations of LIBs and ensure reliable energy storage in harsh environments.