This bibliometric study analyzed 1,261 publications on ovarian cancer care from 2000 to 2023, revealing key research clusters, international collaboration gaps, and emerging trends. The U.S. led in publications, with hotspots including quality of life, surgery, and paclitaxel therapy. Findings highlight the need for multidisciplinary approaches and stronger global cooperation to improve patient outcomes.

In chronic viral infection and cancer, CD8⁺ T killer cells often lapse into “exhausted cells” that no longer can stem disease. Researchers show that a transcriptional repressor called Gfi1, or growth factor independent-1, is a key regulator of the subset formation of exhausted CD8⁺ T cells and may offer a key to reducing exhaustion.