EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 11-Jul-2025 00:10 ET (11-Jul-2025 04:10 GMT/UTC)

Advancing lung cancer treatment: Understanding the differences between LUAD and LUSC

Compuscript Ltd
Peer-Reviewed Publication

Lung cancer remains one of the leading causes of cancer-related mortality, with lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) representing the most prevalent subtypes of non-small cell lung cancer (NSCLC). Despite their classification under the same umbrella, these two forms of lung cancer exhibit distinct genetic landscapes, therapeutic targets, and treatment responses.

Journal: Genes & Diseases

Unlocking the hidden proteome: The role of coding circular RNA in cancer

Compuscript Ltd
Peer-Reviewed Publication

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies. Once thought to be noncoding RNA, circRNA has now been shown to encode functional proteins, challenging conventional RNA biology and opening up novel therapeutic possibilities.

Journal: Genes & Diseases
Funder: National Natural Science Foundation of China, Shandong Provincial Natural Science Foundation of China, Shandong Provincial Natural Science Foundation of China, Shandong Provincial Natural Science Foundation of China, Shandong Provincial Natural Science Foundation of China, Special Funds for Scientific Research on Breast Diseases of Shandong Medical Association of China

Effort seeks to increase cancer-gene testing in primary care

University of Washington School of Medicine/UW Medicine
Peer-Reviewed Publication

Up to 10% of cancers are caused by genes that can be easily detected by commercially available tests. These include such common cancers as cancer of the breast, ovary, colon, stomach, uterus and pancreas. In the JAMA Network Open study published today, Dr. Elizabeth Swisher and colleagues assessed two ways that primary-care practices could assess patients’ hereditary cancer risks and deliver testing to those identified as higher risk.

Journal: JAMA Network Open
Funder: National Institute of Health Sciences

Professor Robert T. Schooley to deliver keynote at the 8th World Congress on Targeting Phage Therapy 2025

Mitochondria-Microbiota Task Force
Meeting Announcement

It is a great pleasure to announce that Professor Robert T. Schooley, from the University of California, San Diego (USA), will be a keynote speaker at the 8th World Congress on Targeting Phage Therapy, scheduled for June 10-11, 2025, in Berlin.

UT Health San Antonio develops drug found to more than double survival time for glioblastoma patients

University of Texas Health Science Center at San Antonio
Peer-Reviewed Publication

Researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have developed a drug shown to significantly extend survival time for patients with glioblastoma, the most common primary brain tumor in adults, according to results of a new trial.

Journal: Nature Communications

Oncomicrobial vaccines mitigate tumor progression via precisely targeting oncomicrobes in mice

Higher Education Press
Peer-Reviewed Publication

This study explores the potential of oncomicrobial vaccines in mitigating tumor progression by targeting specific cancer-promoting microbes in mice. The researchers developed and tested vaccines against Campylobacter jejuni (C. jejuni) and enterotoxigenic Bacteroides fragilis (ETBF), both of which are associated with colorectal cancer (CRC). The vaccines effectively reduced the colonization of these oncomicrobes, suppressed tumor development, and mitigated inflammation without significantly disrupting the gut microbiota. The findings suggest that oncomicrobial vaccines could be a promising strategy for preventing and treating CRC, particularly in individuals at high risk due to family history or other factors.

Journal: Protein & Cell
Funder: National Key Research and Development Program of China, National Natural Science Foundation of China, Shenzhen Science and Technology Programs

Large study of dietary habits suggests more plant oils, less butter could lead to better health

Mass General Brigham
Peer-Reviewed Publication

Mass General Brigham-led researchers investigated data from over 200,000 individuals who were followed for more than 30 years, and found that higher intake of plant-based oils, especially soybean, canola, and olive oil, was associated with lower total, cancer, and cardiovascular disease mortality, whereas butter intake was associated with increased risk of total and cancer mortality. The researchers also found that less than a tablespoon of butter per day with equivalent calories of plant-based oils could lower cancer deaths and overall mortality by 17%.

Journal: JAMA Internal Medicine
Funder: NIH/National Institutes of Health
Meeting: American Heart Association EPI/Lifestyle Scientific Sessions

Study looks to reduce opioid use, optimize pain management after mastectomy

University of Cincinnati
Grant and Award Announcement

A multidisciplinary team of University of Cincinnati Cancer Center researchers is leading a new clinical trial aimed to optimize pain management and reduce the need for opioids after mastectomy procedures.

Funder: Ride Cincinnati Foundation, University of Cincinnati Cancer Center

Chemo-immunotherapy approach shows potential benefit in patients with advanced HPV-negative head and neck cancer

University of Chicago Medical Center
Peer-Reviewed Publication

Chemotherapy and immunotherapy followed by de-escalated chemoradiation showed increased survival and reduced side effects in aggressive head and neck cancers that are not associated with human papillomavirus (HPV) infection, according to a new study.

Journal: JAMA Oncology

BU researchers uncover links between metabolism and aggressive breast cancer

Boston University School of Medicine
Peer-Reviewed Publication

More than 120 million Americans suffer from diabetes or pre-diabetes. Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer, and TNBC patients with obesity-driven diabetes often have worse outcomes.

A new study by researchers from Boston University Chobanian & Avedisian School of Medicine helps explain why this happens and suggests a potential way to improve treatment for these patients.

Journal: Molecular Cancer Research