This article provides a comprehensive review of the bone effects of the main anti-cancer therapies currently in use. The review goes beyond glucocorticoids and hormone therapies and discusses for each drug category what is known regarding cellular effects, BMD effects, and fracture incidence. The review was conducted by an international team of 14 experts across Europe, Australia, Canada, South Africa, and the Middle East. It highlights the pressing need to address cancer treatment-induced bone loss (CTIBL), including in patients undergoing cutting-edge therapies.

Altum Sequencing, a start-up supported by the C3N-IA Science Park at Universidad Carlos III de Madrid (UC3M) and specialized in oncology, has developed a tool to monitor treatment response in patients with solid tumours from a simple blood sample. This advance could represent a turning point in post-treatment follow-up. 

In a paper published in MedComm - Oncology, an international team of scientists summarized the regulatory roles of MRPs in cancer. They further predict the clinical value of MRPs based on data from The Human Protein Atlas and the BEST to explore the correlation between all members of MRPs and the prognosis of patients with cancer. Finally, they provided novel insights regarding strategies targeting MRPs and future directions of research on MRPs and cancer.

This study is the first to reveal the dual regulatory role of copper metabolism imbalance and cuproptosis in the development of inflammatory bowel disease (IBD) and colorectal cancer (CRC), providing novel molecular targets and therapeutic strategies for targeting the cuproptosis pathway and its key regulatory genes in the treatment of IBD and CRC. The related findings were published in Research under the title "Unveiling the Cuproptosis in Colitis and Colitis-Related Carcinogenesis: A Multifaceted Player and Immune Moderator."

The state of Texas awarded UTHealth Houston School of Public Health $5 million over two years for early detection and research, led by principal investigator Jooyeon Hwang, PhD, associate professor in the Department of Environmental and Occupational Health Sciences, on cancer risk among firefighters in Texas. 

A team of researchers at The University of Texas at Arlington has received a grant from the Cancer Prevention and Research Institute of Texas, known as CPRIT, to tackle the critical issue of low physical activity among cancer survivors.[CJM1]  Regular exercise can significantly improve survivors’ quality of life and reduce their risk of death, yet up to 84% don’t get enough to see these benefits.[CJM2] 

A physician-scientist at Sylvester Comprehensive Cancer Center has released a preclinical study highlighting a potential new way to treat colorectal cancer, and has secured a prestigious Stanley J. Glaser Foundation Research Award to continue the research. The findings appear online first in Cancer Research, a journal of the American Association for Cancer Research.